P01282: VIP peptides

General Information

Protein names	- VIP peptides - Intestinal peptide PHV-42 - Peptide histidine valine 42 - Intestinal peptide PHM-27 - Peptide histidine methioninamide 27 - Vasoactive intestinal peptide - VIP - Vasoactive intestinal polypeptide
Gene names	VIP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P01282

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDTRNKAQLL VLLTLLSVLF SQTSAWPLYR APSALRLGDR IPFEGANEPD QVSLKEDIDM
        70         80         90        100        110        120
LQNALAENDT PYYDVSRNAR HADGVFTSDF SKLLGQLSAK KYLESLMGKR VSSNISEDPV
       130        140        150        160        170
PVKRHSDAVF TDNYTRLRKQ MAVKKYLNSI LNGKRSSEGE SPDFPEELEK

Isoforms

- Isoform 2 of VIP peptides

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P01282-1-unknown	MDTRNK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt94175
P01282-21-unknown	SQTSAW...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P01282-21-unknown	SQTSAW...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112775
P01282-128-unknown	AVFTDN...	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31689
P01282-128-unknown	AVFTDN...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143789
P01282-131-unknown	TDNYTR...	131	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31691
P01282-131-unknown	TDNYTR...	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143913
P01282-133-unknown	NYTRLR...	133	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31693
P01282-133-unknown	NYTRLR...	133	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143981

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KRHSDA	127	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31689
...SDAVFT	130	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31691
...AVFTDN	132	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31693
...EELEK	170	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89793

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
THOP1_HUMAN	127	HSDA.\|.AVFT	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
THOP1_HUMAN	130	AVFT.\|.TDNY	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
THOP1_HUMAN	132	FTDN.\|.NYTR	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)