P04843: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

General Information

Protein names	- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit - Ribophorin I - RPN-I - Ribophorin-1
Gene names	RPN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P04843

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEAPAAGLFL LLLLGTWAPA PGSASSEAPP LINEDVKRTV DLSSHLAKVT AEVVLAHLGG
        70         80         90        100        110        120
GSTSRATSFL LALEPELEAR LAHLGVQVKG EDEEENNLEV RETKIKGKSG RFFTVKLPVA
       130        140        150        160        170        180
LDPGAKISVI VETVYTHVLH PYPTQITQSE KQFVVFEGNH YFYSPYPTKT QTMRVKLASR
       190        200        210        220        230        240
NVESYTKLGN PTRSEDLLDY GPFRDVPAYS QDTFKVHYEN NSPFLTITSM TRVIEVSHWG
       250        260        270        280        290        300
NIAVEENVDL KHTGAVLKGP FSRYDYQRQP DSGISSIRSF KTILPAAAQD VYYRDEIGNV
       310        320        330        340        350        360
STSHLLILDD SVEMEIRPRF PLFGGWKTHY IVGYNLPSYE YLYNLGDQYA LKMRFVDHVF
       370        380        390        400        410        420
DEQVIDSLTV KIILPEGAKN IEIDSPYEIS RAPDELHYTY LDTFGRPVIV AYKKNLVEQH
       430        440        450        460        470        480
IQDIVVHYTF NKVLMLQEPL LVVAAFYILF FTVIIYVRLD FSITKDPAAE ARMKVACITE
       490        500        510        520        530        540
QVLTLVNKRI GLYRHFDETV NRYKQSRDIS TLNSGKKSLE TEHKALTSEI ALLQSRLKTE
       550        560        570        580        590        600
GSDLCDRVSE MQKLDAQVKE LVLKSAVEAE RLVAGKLKKD TYIENEKLIS GKRQELVTKI

DHILDAL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P04843-23-unknown	SASSEA...	23		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04843-23-unknown	SASSEA...	23		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04843-23-	SASSEA...	23		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04843-24-unknown	ASSEAP...	24	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P04843-24-	ASSEAP...	24		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04843-25-unknown	SSEAPP...	25		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04843-25-unknown	SSEAPP...	25		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P04843-25-	SSEAPP...	25		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P04843-173-unknown	MRVKLA...	173	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417529

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ILDAL	607	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)