TopFIND 4.0

P04925: Major prion protein

General Information

Protein names
- Major prion protein
- PrP
- PrP27-30
- PrP33-35C
- CD230
Gene names Prnp
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P04925

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MANLGYWLLA LFVTMWTDVG LCKKRPKPGG WNTGGSRYPG QGSPGGNRYP PQGGTWGQPH 
        70         80         90        100        110        120 
GGGWGQPHGG SWGQPHGGSW GQPHGGGWGQ GGGTHNQWNK PSKPKTNLKH VAGAAAAGAV 
       130        140        150        160        170        180 
VGGLGGYMLG SAMSRPMIHF GNDWEDRYYR ENMYRYPNQV YYRPVDQYSN QNNFVHDCVN 
       190        200        210        220        230        240 
ITIKQHTVTT TTKGENFTET DVKMMERVVE QMCVTQYQKE SQAYYDGRRS SSTVLFSSPP 
       250    
VILLISFLIF LIVG

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P04925-23-unknown KKRPKP... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P04925-228-unknown RRSSST... 228 inferred from cleavage unknown TopFIND Inferred from cleavage TC27836

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)