TopFIND 4.0

O35598: Disintegrin and metalloproteinase domain-containing protein 10

General Information

Protein names
- Disintegrin and metalloproteinase domain-containing protein 10
- ADAM 10
- 3.4.24.81 {ECO:0000269|PubMed:17245433}
- Kuzbanian protein homolog
- Mammalian disintegrin-metalloprotease
- CD156c
Gene names Adam10
Organism Mus musculus
Protease Family M12.210
Protease ID M12.210
Chromosome location
UniProt ID O35598

3

N-termini

2

C-termini

0

Cleavages

21

Substrates

Sequence

        10         20         30         40         50         60 
MVLPTVLILL LSWAAGLGGQ YGNPLNKYIR HYEGLSYNVD SLHQKHQRAK RAVSHEDQFL 
        70         80         90        100        110        120 
LLDFHAHGRQ FNLRMKRDTS LFSDEFKVET SNKVLDYDTS HIYTGHIYGE EGSFSHGSVI 
       130        140        150        160        170        180 
DGRFEGFIKT RGGTFYIEPA ERYIKDRILP FHSVIYHEDD INYPHKYGPQ GGCADHSVFE 
       190        200        210        220        230        240 
RMRKYQMTGV EEGARAHPEK HAASSGPELL RKKRTTLAER NTCQLYIQTD HLFFKYYGTR 
       250        260        270        280        290        300 
EAVIAQISSH VKAIDTIYQT TDFSGIRNIS FMVKRIRINT TSDEKDPTNP FRFPNIGVEK 
       310        320        330        340        350        360 
FLELNSEQNH DDYCLAYVFT DRDFDDGVLG LAWVGAPSGS SGGICEKSKL YSDGKKKSLN 
       370        380        390        400        410        420 
TGIITVQNYG SHVPPKVSHI TFAHEVGHNF GSPHDSGTEC TPGESKNLGQ KENGNYIMYA 
       430        440        450        460        470        480 
RATSGDKLNN NKFSLCSIRN ISQVLEKKRN NCFVESGQPI CGNGMVEQGE ECDCGYSDQC 
       490        500        510        520        530        540 
KDDCCFDANQ PEGKKCKLKP GKQCSPSQGP CCTAQCAFKS KSEKCRDDSD CAKEGICNGF 
       550        560        570        580        590        600 
TALCPASDPK PNFTDCNRHT QVCINGQCAG SICEKYDLEE CTCASSDGKD DKELCHVCCM 
       610        620        630        640        650        660 
KKMAPSTCAS TGSLQWSKQF SGRTITLQPG SPCNDFRGYC DVFMRCRLVD ADGPLARLKK 
       670        680        690        700        710        720 
AIFSPQLYEN IAEWIVAHWW AVLLMGIALI MLMAGFIKIC SVHTPSSNPK LPPPKPLPGT 
       730        740    
LKRRRPPQPI QQPPRQRPRE SYQMGHMRR

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 21 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates