P07355: Annexin A2

General Information

Protein names	- Annexin A2 - Annexin II - Annexin-2 - Calpactin I heavy chain - Calpactin-1 heavy chain - Chromobindin-8 - Lipocortin II - Placental anticoagulant protein IV - PAP-IV - Protein I - p36
Gene names	ANXA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P07355

14 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTVHEILCK LSLEGDHSTP PSAYGSVKAY TNFDAERDAL NIETAIKTKG VDEVTIVNIL
        70         80         90        100        110        120
TNRSNAQRQD IAFAYQRRTK KELASALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG
       130        140        150        160        170        180
LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA
       190        200        210        220        230        240
EDGSVIDYEL IDQDARDLYD AGVKRKGTDV PKWISIMTER SVPHLQKVFD RYKSYSPYDM
       250        260        270        280        290        300
LESIRKEVKG DLENAFLNLV QCIQNKPLYF ADRLYDSMKG KGTRDKVLIR IMVSRSEVDM
       310        320        330
LKIRSEFKRK YGKSLYYYIQ QDTKGDYQKA LLYLCGGDD

Isoforms

- Isoform 2 of Annexin A2

Sequence View

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Protein Neighborhood

Domains & Features

14 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P07355-1-unknown	MSTVHE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107566
P07355-2-unknown	MSTVHE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07355-2-Acetylation	STVHEI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07355-2-Acetylation	STVHEI...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P07355-2-Acetylation	STVHEI...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111451
P07355-11-unknown	LSLEGD...	11		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23999
P07355-11-unknown	LSLEGD...	11		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194911
P07355-12-unknown	SLEGDH...	12		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164436
P07355-12-	SLEGDH...	12			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P07355-12-	SLEGDH...	12			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P07355-12-	SLEGDH...	12			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P07355-17-unknown	HSTPPS...	17		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175343
P07355-17-	HSTPPS...	17			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P07355-17-	HSTPPS...	17			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P07355-29-unknown	AYTNFD...	29		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175341
P07355-29-	AYTNFD...	29			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P07355-48-unknown	TKGVDE...	48		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164434
P07355-48-	TKGVDE...	48			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P07355-48-	TKGVDE...	48			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P07355-48-	TKGVDE...	48			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P07355-184-	SVIDYE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07355-184-	SVIDYE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P07355-184-	SVIDYE...	184			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P07355-184-unknown	SVIDYE...	184		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172601

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EILCKL	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23999
...CGGDD	339	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...CGGDD	339	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62725

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP7_HUMAN	10	LCKL.\|.LSLE	inferred from experiment	unknown	MEROPS	Miyazaki K	Tsunezumi J et al.:Matrilysin (matrix metalloprote... (M10.008)	18721140,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)