P09110: 3-ketoacyl-CoA thiolase, peroxisomal

General Information

Protein names	- 3-ketoacyl-CoA thiolase, peroxisomal - 2.3.1.16 - Acetyl-CoA acyltransferase - Beta-ketothiolase - Peroxisomal 3-oxoacyl-CoA thiolase
Gene names	ACAA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09110

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT
        70         80         90        100        110        120
PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN
       130        140        150        160        170        180
RQCSSGLQAV ASIAGGIRNG SYDIGMACGV ESMSLADRGN PGNITSRLME KEKARDCLIP
       190        200        210        220        230        240
MGITSENVAE RFGISREKQD TFALASQQKA ARAQSKGCFQ AEIVPVTTTV HDDKGTKRSI
       250        260        270        280        290        300
TVTQDEGIRP STTMEGLAKL KPAFKKDGST TAGNSSQVSD GAAAILLARR SKAEELGLPI
       310        320        330        340        350        360
LGVLRSYAVV GVPPDIMGIG PAYAIPVALQ KAGLTVSDVD IFEINEAFAS QAAYCVEKLR
       370        380        390        400        410        420
LPPEKVNPLG GAVALGHPLG CTGARQVITL LNELKRRGKR AYGVVSMCIG TGMGAAAVFE

YPGN

Isoforms

- Isoform 2 of 3-ketoacyl-CoA thiolase, peroxisomal

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09110-1-unknown	MQRLQV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92095
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P09110-27-	LSGAPQ...	27		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P09110-27-unknown	LSGAPQ...	27	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09110-27-unknown	LSGAPQ...	27		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09110-27-unknown	LSGAPQ...	27	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt114306

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EYPGN	424	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...EYPGN	424	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87713

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)