TopFIND 4.0

P09669: Cytochrome c oxidase subunit 6C

General Information

Protein names	- Cytochrome c oxidase subunit 6C - Cytochrome c oxidase polypeptide VIc
Gene names	COX6C
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09669

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MAPEVLPKPR MRGLLARRLR NHMAVAFVLS LGVAALYKFR VADQRKKAYA DFYRNYDVMK
70
DFEEMRKAGI FQSVK

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P09669-1-	MAPEVL...	1			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P09669-1-unknown	MAPEVL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09669-1-unknown	MAPEVL...	1			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09669-1-unknown	MAPEVL...	1			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P09669-2-unknown	APEVLP...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...FQSVK	75		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...FQSVK	75		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...FQSVK	75	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...FQSVK	75		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...FQSVK	75		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)