P10107: Annexin A1

General Information

Protein names	- Annexin A1 - Annexin I - Annexin-1 - Calpactin II - Calpactin-2 - Chromobindin-9 - Lipocortin I {ECO:0000303\|PubMed:2974946} - Phospholipase A2 inhibitory protein - p35
Gene names	Anxa1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P10107

14 N-termini

11 C-termini

17 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAMVSEFLKQ ARFLENQEQE YVQAVKSYKG GPGSAVSPYP SFNVSSDVAA LHKAIMVKGV
        70         80         90        100        110        120
DEATIIDILT KRTNAQRQQI KAAYLQENGK PLDEVLRKAL TGHLEEVVLA MLKTPAQFDA
       130        140        150        160        170        180
DELRGAMKGL GTDEDTLIEI LTTRSNEQIR EINRVYREEL KRDLAKDITS DTSGDFRKAL
       190        200        210        220        230        240
LALAKGDRCQ DLSVNQDLAD TDARALYEAG ERRKGTDVNV FTTILTSRSF PHLRRVFQNY
       250        260        270        280        290        300
GKYSQHDMNK ALDLELKGDI EKCLTTIVKC ATSTPAFFAE KLYEAMKGAG TRHKALIRIM
       310        320        330        340
VSRSEIDMNE IKVFYQKKYG ISLCQAILDE TKGDYEKILV ALCGGN

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

14 N-termini - 11 C-termini - 17 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P10107-2-unknown	MAMVSE...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P10107-2-unknown	MAMVSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P10107-2-Acetylation	AMVSEF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P10107-2-Acetylation	AMVSEF...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P10107-2-Acetylation	AMVSEF...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P10107-2-Acetylation	AMVSEF...	2	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P10107-2-Acetylation	AMVSEF...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P10107-4-unknown	VSEFLK...	4		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29672
P10107-7-unknown	FLKQAR...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28738
P10107-63-unknown	ATIIDI...	63		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29673
P10107-78-Pyrrolidone carboxylic acid	QQIKAA...	78	pyrrolidone carboxylic acid-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P10107-110-unknown	AMLKTP...	110		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28739
P10107-110-unknown	AMLKTP...	110		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29674
P10107-112-unknown	LKTPAQ...	112		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28740
P10107-112-unknown	LKTPAQ...	112		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29675
P10107-138-unknown	IEILTT...	138		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29676
P10107-181-unknown	LALAKG...	181		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28741
P10107-181-unknown	LALAKG...	181		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29677
P10107-193-unknown	SVNQDL...	193		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28742
P10107-193-unknown	SVNQDL...	193		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29678
P10107-222-unknown	TTILTS...	222		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29679
P10107-278-unknown	FAEKLY...	278		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28743
P10107-278-unknown	FAEKLY...	278		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29680
P10107-283-unknown	YEAMKG...	283		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28744
P10107-283-unknown	YEAMKG...	283		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29681

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AMVSEF	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28738
...KGVDEA	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29673
...EEVVLA	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28739
...EEVVLA	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29674
...VVLAML	111	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28740
...VVLAML	111	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29675
...DEDTLI	137	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29676
...FRKALL	180	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28741
...FRKALL	180	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29677
...RCQDLS	192	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28742
...RCQDLS	192	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29678
...DVNVFT	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29679
...STPAFF	277	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28743
...STPAFF	277	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29680
...FAEKLY	282	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28744
...FAEKLY	282	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29681
...LCGGN	346	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	3	MAMV.\|.VSEF	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @3
CATD_MOUSE	6	VSEF.\|.FLKQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @6
CATE_MOUSE	62	VDEA.\|.ATII	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @62
CATD_MOUSE	109	VVLA.\|.AMLK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @109
CATE_MOUSE	109	VVLA.\|.AMLK	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @109
CATD_MOUSE	111	LAML.\|.LKTP	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @111
CATE_MOUSE	111	LAML.\|.LKTP	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @111
CATE_MOUSE	137	DTLI.\|.IEIL	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @137
CATD_MOUSE	180	KALL.\|.LALA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @180
CATE_MOUSE	180	KALL.\|.LALA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @180
CATD_MOUSE	192	QDLS.\|.SVNQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @192
CATE_MOUSE	192	QDLS.\|.SVNQ	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @192
CATE_MOUSE	221	NVFT.\|.TTIL	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @221
CATD_MOUSE	277	PAFF.\|.FAEK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @277
CATE_MOUSE	277	PAFF.\|.FAEK	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @277
CATD_MOUSE	282	EKLY.\|.YEAM	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> ANXA1_MOUSE @282
CATE_MOUSE	282	EKLY.\|.YEAM	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> ANXA1_MOUSE @282

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)