P13073: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

General Information

Protein names	- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial - Cytochrome c oxidase polypeptide IV - Cytochrome c oxidase subunit IV isoform 1 - COX IV-1
Gene names	COX4I1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P13073

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLATRVFSLV GKRAISTSVC VRAHESVVKS EDFSLPAYMD RRDHPLPEVA HVKHLSASQK
        70         80         90        100        110        120
ALKEKEKASW SSLSMDEKVE LYRIKFKESF AEMNRGSNEW KTVVGGAMFF IGFTALVIMW
       130        140        150        160
QKHYVYGPLP QSFDKEWVAK QTKRMLDMKV NPIQGLASKW DYEKNEWKK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P13073-23-unknown	AHESVV...	23	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P13073-23-unknown	AHESVV...	23		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P13073-23-unknown	AHESVV...	23		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P13073-23-	AHESVV...	23		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P13073-39-unknown	MDRRDH...	39	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000455301

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MDRRDH	43	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454869
...TKRMLD	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455301
...NEWKK	169	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)