P14152: Malate dehydrogenase, cytoplasmic

General Information

Protein names	- Malate dehydrogenase, cytoplasmic - 1.1.1.37 - Cytosolic malate dehydrogenase
Gene names	Mdh1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P14152

6 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC
        70         80         90        100        110        120
ALPLLQDVIA TDKEEIAFKD LDVAVLVGSM PRREGMERKD LLKANVKIFK SQGTALEKYA
       130        140        150        160        170        180
KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKSQIALK LGVTADDVKN
       190        200        210        220        230        240
VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFITTVQQR GAAVIKARKL
       250        260        270        280        290        300
SSAMSAAKAI ADHIRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV
       310        320        330
EGLPINDFSR EKMDLTAKEL TEEKETAFEF LSSA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14152-2-unknown	MSEPIR...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P14152-2-unknown	MSEPIR...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14152-2-Acetylation	SEPIRV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14152-2-Acetylation	SEPIRV...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P14152-4-unknown	PIRVLV...	4		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P14152-82-unknown	DVAVLV...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29712
P14152-82-unknown	DVAVLV...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28765
P14152-224-unknown	ITTVQQ...	224		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29713
P14152-224-unknown	ITTVQQ...	224		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28766
P14152-300-unknown	VEGLPI...	300			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AFKDLD	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29712
...AFKDLD	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28765
...NFSCLT	155	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119816
...LKGEFI	223	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29713
...LKGEFI	223	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28766
...FLSSA	334	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	81	KDLD.\|.DVAV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> MDHC_MOUSE @81
CATD_MOUSE	81	KDLD.\|.DVAV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> MDHC_MOUSE @81
CATE_MOUSE	223	GEFI.\|.ITTV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> MDHC_MOUSE @223
CATD_MOUSE	223	GEFI.\|.ITTV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> MDHC_MOUSE @223

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)