P14685: 26S proteasome non-ATPase regulatory subunit 3

General Information

Protein names	- 26S proteasome non-ATPase regulatory subunit 3 - 26S proteasome regulatory subunit RPN3 - 26S proteasome regulatory subunit S3 - Proteasome subunit p58 - Transplantation antigen P91A - Tum-P91A antigen
Gene names	Psmd3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P14685

5 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKQEGSARRR GADKAKPPPG GEQEPPPPAP QDVEMKEEAA AGSGSTGEGD GKAAATEHSQ
        70         80         90        100        110        120
RELDTVTLED IKEHVRQLEK AVSGKEPRFV LRALRMLPST SRRLNHYVLY KAVHGFFTSN
       130        140        150        160        170        180
NATRDFLLPF LEEPMDTEAD LQFRPRTGKA ASAPLLPEVE AYLQLLMVIF LMNSKRYKEA
       190        200        210        220        230        240
QKISDDLMQK ISTQNRRALD LVAAKCYYYH ARVYEFLDKL DVVRSFLHAR LRTATLRHDA
       250        260        270        280        290        300
DGQATLLNLL LRNYLHYSLY DQAEKLVSKS VFPEQANNNE WARYLYYTGR IKAIQLEYSE
       310        320        330        340        350        360
ARRTMTNALR KAPQHTAVGF KQTVHKLLIV VELLLGEIPD RLQFRQPSLK RSLMPYFLLT
       370        380        390        400        410        420
QAVRTGNLAK FNQVLDQFGE KFQTDGTYTL IIRLRHNVIK TGVRMISLSY SRISLADIAQ
       430        440        450        460        470        480
KLQLDSPEDA EFIVAKAIRD GVIEASINHE KGYVQSKEMI DIYSTREPQL AFHQRISFCL
       490        500        510        520        530
DIHNMSVKAM RFPPKSYNKD LESAEERRER EQQDLEFAKE MAEDDDDSFP

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14685-1-unknown	MKQEGS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14685-1-acetylation	MKQEGS...	1	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P14685-51-unmodified	GKAAAT...	51			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P14685-69-unknown	EDIKEH...	69		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P14685-497-unknown	YNKDLE...	497		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33365

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SYSRIS	413	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116968
...FPPKSY	496	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33365
...DDSFP	530	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	496	PKSY.\|.YNKD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)