TopFIND 4.0

P15144: Aminopeptidase N {ECO:0000305}

General Information

Protein names
- Aminopeptidase N {ECO:0000305}
- AP-N
- hAPN
- 3.4.11.2 {ECO:0000269|PubMed:22932899, ECO:0000269|PubMed:6149934, ECO:0000269|PubMed:7576235, ECO:0000269|PubMed:8887485}
- Alanyl aminopeptidase
- Aminopeptidase M
- AP-M
- Microsomal aminopeptidase
- Myeloid plasma membrane glycoprotein CD13
- gp150
- CD13
Gene names ANPEP
Organism Homo sapiens
Protease Family M01.001
Protease ID M01.001
Chromosome location
UniProt ID P15144

1

N-termini

3

C-termini

0

Cleavages

2

Substrates

Sequence

        10         20         30         40         50         60 
MAKGFYISKS LGILGILLGV AAVCTIIALS VVYSQEKNKN ANSSPVASTT PSASATTNPA 
        70         80         90        100        110        120 
SATTLDQSKA WNRYRLPNTL KPDSYRVTLR PYLTPNDRGL YVFKGSSTVR FTCKEATDVI 
       130        140        150        160        170        180 
IIHSKKLNYT LSQGHRVVLR GVGGSQPPDI DKTELVEPTE YLVVHLKGSL VKDSQYEMDS 
       190        200        210        220        230        240 
EFEGELADDL AGFYRSEYME GNVRKVVATT QMQAADARKS FPCFDEPAMK AEFNITLIHP 
       250        260        270        280        290        300 
KDLTALSNML PKGPSTPLPE DPNWNVTEFH TTPKMSTYLL AFIVSEFDYV EKQASNGVLI 
       310        320        330        340        350        360 
RIWARPSAIA AGHGDYALNV TGPILNFFAG HYDTPYPLPK SDQIGLPDFN AGAMENWGLV 
       370        380        390        400        410        420 
TYRENSLLFD PLSSSSSNKE RVVTVIAHEL AHQWFGNLVT IEWWNDLWLN EGFASYVEYL 
       430        440        450        460        470        480 
GADYAEPTWN LKDLMVLNDV YRVMAVDALA SSHPLSTPAS EINTPAQISE LFDAISYSKG 
       490        500        510        520        530        540 
ASVLRMLSSF LSEDVFKQGL ASYLHTFAYQ NTIYLNLWDH LQEAVNNRSI QLPTTVRDIM 
       550        560        570        580        590        600 
NRWTLQMGFP VITVDTSTGT LSQEHFLLDP DSNVTRPSEF NYVWIVPITS IRDGRQQQDY 
       610        620        630        640        650        660 
WLIDVRAQND LFSTSGNEWV LLNLNVTGYY RVNYDEENWR KIQTQLQRDH SAIPVINRAQ 
       670        680        690        700        710        720 
IINDAFNLAS AHKVPVTLAL NNTLFLIEER QYMPWEAALS SLSYFKLMFD RSEVYGPMKN 
       730        740        750        760        770        780 
YLKKQVTPLF IHFRNNTNNW REIPENLMDQ YSEVNAISTA CSNGVPECEE MVSGLFKQWM 
       790        800        810        820        830        840 
ENPNNNPIHP NLRSTVYCNA IAQGGEEEWD FAWEQFRNAT LVNEADKLRA ALACSKELWI 
       850        860        870        880        890        900 
LNRYLSYTLN PDLIRKQDAT STIISITNNV IGQGLVWDFV QSNWKKLFND YGGGSFSFSN 
       910        920        930        940        950        960 
LIQAVTRRFS TEYELQQLEQ FKKDNEETGF GSGTRALEQA LEKTKANIKW VKENKEVVLQ 
   
WFTENSK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 2 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P15144-2-unknown AKGFYI... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates