P16014: Secretogranin-1

General Information

Protein names	- Secretogranin-1 - Chromogranin-B - CgB - Secretogranin I - SgI - CCB peptide - PE-11
Gene names	Chgb
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P16014

12 N-termini

12 C-termini

15 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQPAMLLGLL GAAALAAVSS APVDNRDHNE EMVTRCIIEV LSNALSKSSV PTITPECRQV
        70         80         90        100        110        120
LKKSGKEVKG EEKGENQNSK FEVRLLRDPA DASGTRWASS REDAGAPVED SQGQTKVGNE
       130        140        150        160        170        180
KWTEGGGHSR EGVDDQESLR PSNQQASKEA KIYHSEERVG KEREKEEGKI YPMGEHREDA
       190        200        210        220        230        240
GEEKKHIEDS GEKPNTFSNK RSEASAKKKD ESVARADAHS MELEEKTHSR EQSSQESGEE
       250        260        270        280        290        300
TRRQEKPQEL TDQDQSQEES QEGEEGEEGE EGEEGEEDSA SEVTKRRPRH HHGRSGSNKS
       310        320        330        340        350        360
SYEGHPLSEE RRPSPKESKE ADVATVRLGE KRSHHLAHYR ASEEEPEYGE ESRSYRGLQY
       370        380        390        400        410        420
RGRGSEEDRA PRPRSEESQE REYKRNHPDS ELESTANRHG EETEEERSYE GANGRQHRGR
       430        440        450        460        470        480
GREPGAHSAL DTREEKRLLD EGHYPVRESP IDTAKRYPQS KWQEQEKNYL NYGEEGDQGR
       490        500        510        520        530        540
WWQQEEQLGP EESREEVRFP DRQYEPYPIT EKRKRLGALF NPYFDPLQWK NSDFEKRGNP
       550        560        570        580        590        600
DDSFLEDEGE DRNGVTLTEK NSFPEYNYDW WERRPFSEDV NWGYEKRSFA RAPQLDLKRQ
       610        620        630        640        650        660
YDGVAELDQL LHYRKKADEF PDFYDSEEQM GPHQEANDEK ARADQRVLTA EEKKELENLA
       670
AMDLELQKIA EKFSQRG

Isoforms

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P16014-21-unknown	APVDNR...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P16014-86-unknown	LRDPAD...	86	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31490
P16014-438-unknown	LLDEGH...	438	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34686
P16014-446-unknown	VRESPI...	446	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31491
P16014-454-unknown	AKRYPQ...	454	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31492
P16014-454-unknown	AKRYPQ...	454	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31437
P16014-457-unknown	YPQSKW...	457	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34687
P16014-516-unknown	LGALFN...	516	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34688
P16014-538-unknown	GNPDDS...	538	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34689
P16014-575-unknown	PFSEDV...	575	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34657
P16014-575-unknown	PFSEDV...	575	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34690
P16014-588-unknown	SFARAP...	588	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34658
P16014-588-unknown	SFARAP...	588	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34691
P16014-592-unknown	APQLDL...	592	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34692
P16014-613-unknown	YRKKAD...	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31493
P16014-613-unknown	YRKKAD...	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31438

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FEVRLL	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31490
...REEKRL	437	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34686
...EGHYPV	445	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31491
...SPIDTA	453	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31492
...SPIDTA	453	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31437
...DTAKRY	456	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34687
...EKRKRL	515	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34688
...DFEKRG	537	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34689
...WWERRP	574	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34657
...WWERRP	574	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34690
...GYEKRS	587	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34658
...GYEKRS	587	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34691
...RSFARA	591	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34692
...DQLLHY	612	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31493
...DQLLHY	612	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31438
...FSQRG	677	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA6_MOUSE	85	VRLL.\|.LRDP	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
NEC2_MOUSE	437	EKRL.\|.LLDE	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
CBPA6_MOUSE	445	HYPV.\|.VRES	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
CBPA6_MOUSE	453	IDTA.\|.AKRY	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
CBPA4_MOUSE	453	IDTA.\|.AKRY	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
NEC2_MOUSE	456	AKRY.\|.YPQS	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
NEC2_MOUSE	515	RKRL.\|.LGAL	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
NEC2_MOUSE	537	EKRG.\|.GNPD	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
NEC1_MOUSE	574	ERRP.\|.PFSE	inferred from experiment	unknown	MEROPS	Winkler H	Laslop A et al.:Proteolytic processing of chrom... (S08.072)	9422384,
NEC2_MOUSE	574	ERRP.\|.PFSE	inferred from experiment	unknown	MEROPS	Winkler H	Laslop A et al.:Proteolytic processing of chrom... (S08.072)	9422384,
NEC1_MOUSE	587	EKRS.\|.SFAR	inferred from experiment	unknown	MEROPS	Winkler H	Laslop A et al.:Proteolytic processing of chrom... (S08.072)	9422384,
NEC2_MOUSE	587	EKRS.\|.SFAR	inferred from experiment	unknown	MEROPS	Winkler H	Laslop A et al.:Proteolytic processing of chrom... (S08.072)	9422384,
NEC2_MOUSE	591	FARA.\|.APQL	inferred from experiment	unknown	MEROPS	Fricker LD	Pan H et al.:The role of prohormone converta... (S08.073)	16903874,
CBPA6_MOUSE	612	LLHY.\|.YRKK	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Substrate specificity of human ... (M14.018)	20855895,
CBPA4_MOUSE	612	LLHY.\|.YRKK	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,

TopFIND

P16014: Secretogranin-1

General Information

12

N-termini

12

C-termini

15

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

12 N-termini - 12 C-termini - 15 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates