TopFIND 4.0

P16043: Somatoliberin

General Information

Protein names	- Somatoliberin - Growth hormone-releasing factor - GRF - Growth hormone-releasing hormone - GHRH
Gene names	Ghrh
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P16043

2

N-termini

1

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MLLWVLFVIL ILTSGSHCSL PPSPPFRMQR HVDAIFTTNY RKLLSQLYAR KVIQDIMNKQ
70 80 90 100
GERIQEQRAR LSRQEDSMWT EDKQMTLESI LQGFPRMKPS ADA

Isoforms

Sequence View

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P16043-20-unknown	LPPSPP...	20		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P16043-74-unknown	QEDSMW...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34693
P16043-74-unknown	QEDSMW...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34760

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ARLSRQ	73	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34693
	...ARLSRQ	73	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34760

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
NEC2_MOUSE	73	LSRQ.\|.QEDS	inferred from experiment	unknown	MEROPS	Steiner DF	Dey A et al.:Furin and prohormone convertase... (S08.073)	14684599,
PCSK5_MOUSE	73	LSRQ.\|.QEDS	inferred from experiment	unknown	MEROPS	Steiner DF	Dey A et al.:Furin and prohormone convertase... (S08.073)	14684599,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)