P17900: Ganglioside GM2 activator

General Information

Protein names	- Ganglioside GM2 activator - Cerebroside sulfate activator protein - GM2-AP - Sphingolipid activator protein 3 - SAP-3 - Ganglioside GM2 activator isoform short
Gene names	GM2A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P17900

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQSLMQAPLL IALGLLLAAP AQAHLKKPSQ LSSFSWDNCD EGKDPAVIRS LTLEPDPIIV
        70         80         90        100        110        120
PGNVTLSVMG STSVPLSSPL KVDLVLEKEV AGLWIKIPCT DYIGSCTFEH FCDVLDMLIP
       130        140        150        160        170        180
TGEPCPEPLR TYGLPCHCPF KEGTYSLPKS EFVVPDLELP SWLTTGNYRI ESVLSSSGKR
       190
LGCIKIAASL KGI

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P17900-24-unknown	HLKKPS...	24	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17900-32-unknown	SSFSWD...	32	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17900-32-	SSFSWD...	32		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P17900-33-	SFSWDN...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P17900-33-	SFSWDN...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P17900-33-	SFSWDN...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P17900-34-unknown	FSWDNC...	34	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17900-34-	FSWDNC...	34		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P17900-34-	FSWDNC...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P17900-34-	FSWDNC...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EPLRTY	131	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000429100
	...SLKGI	193	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)