P20674: Cytochrome c oxidase subunit 5A, mitochondrial

General Information

Protein names	- Cytochrome c oxidase subunit 5A, mitochondrial - Cytochrome c oxidase polypeptide Va
Gene names	COX5A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P20674

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLGAALRRCA VAATTRADPR GLLHSARTPG PAVAIQSVRC YSHGSQETDE EFDARWVTYF
        70         80         90        100        110        120
NKPDIDAWEL RKGINTLVTY DMVPEPKIID AALRACRRLN DFASTVRILE VVKDKAGPHK
       130        140        150
EIYPYVIQEL RPTLNELGIS TPEELGLDKV

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P20674-41-	YSHGSQ...	41		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P20674-42-unknown	SHGSQE...	42	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P20674-42-unknown	SHGSQE...	42		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P20674-42-unknown	SHGSQE...	42		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_CD95	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P20674-42-	SHGSQE...	42		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P20674-43-	HGSQET...	43		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P20674-44-	GSQETD...	44		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P20674-44-	GSQETD...	44		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P20674-44-	GSQETD...	44		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P20674-44-	GSQETD...	44		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P20674-82-unknown	MVPEPK...	82	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456314

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GLDKV	150	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)