P23025: DNA repair protein complementing XP-A cells

General Information

Protein names	- DNA repair protein complementing XP-A cells - Xeroderma pigmentosum group A-complementing protein
Gene names	XPA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P23025

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAADGALPE AAALEQPAEL PASVRASIER KRQRALMLRQ ARLAARPYSA TAAAATGGMA
        70         80         90        100        110        120
NVKAAPKIID TGGGFILEEE EEEEQKIGKV VHQPGPVMEF DYVICEECGK EFMDSYLMNH
       130        140        150        160        170        180
FDLPTCDNCR DADDKHKLIT KTEAKQEYLL KDCDLEKREP PLKFIVKKNP HHSQWGDMKL
       190        200        210        220        230        240
YLKLQIVKRS LEVWGSQEAL EEAKEVRQEN REKMKQKKFD KKVKELRRAV RSSVWKRETI
       250        260        270
VHQHEYGPEE NLEDDMYRKT CTMCGHELTY EKM

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P23025-2-unknown	MAAADG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P23025-2-Acetylation	AAADGA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P23025-2-Acetylation	AAADGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P23025-2-Acetylation	AAADGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P23025-6-	GALPEA...	6			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P23025-6-	GALPEA...	6			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P23025-6-	GALPEA...	6			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P23025-6-	GALPEA...	6			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P23025-6-	GALPEA...	6			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P23025-49-unknown	SATAAA...	49			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P23025-49-	SATAAA...	49			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...TYEKM	273	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)