P28072: Proteasome subunit beta type-6

General Information

Protein names	- Proteasome subunit beta type-6 - 3.4.25.1 {ECO:0000269\|PubMed:27176742} - Macropain delta chain - Multicatalytic endopeptidase complex delta chain - Proteasome delta chain - Proteasome subunit Y
Gene names	PSMB6
Organism	Homo sapiens
Protease Family
Protease ID	T01.010
Chromosome location
UniProt ID	P28072

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAATLLAARG AGPAPAWGPE AFTPDWESRE VSTGTTIMAV QFDGGVVLGA DSRTTTGSYI
        70         80         90        100        110        120
ANRVTDKLTP IHDRIFCCRS GSAADTQAVA DAVTYQLGFH SIELNEPPLV HTAASLFKEM
       130        140        150        160        170        180
CYRYREDLMA GIIIAGWDPQ EGGQVYSVPM GGMMVRQSFA IGGSGSSYIY GYVDATYREG
       190        200        210        220        230
MTKEECLQFT ANALALAMER DGSSGGVIRL AAIAESGVER QVLLGDQIPK FAVATLPPA

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P28072-2-unknown	MAATLL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P28072-2-acetylation	AATLLA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P28072-2-acetylation	AATLLA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P28072-2-acetylation	AATLLA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P28072-35-	TTIMAV...	35			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P28072-35-unknown	TTIMAV...	35		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P28072-54-	TTTGSY...	54			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P28072-101-unknown	SIELNE...	101		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5756

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QLGFHS	100	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5756
	...TLPPA	239	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	100	GFHS.\|.SIEL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)