P30044: Peroxiredoxin-5, mitochondrial

General Information

Protein names	- Peroxiredoxin-5, mitochondrial - 1.11.1.15 {ECO:0000269\|PubMed:10751410} - Alu corepressor 1 - Antioxidant enzyme B166 - AOEB166 - Liver tissue 2D-page spot 71B - PLP - Peroxiredoxin V - Prx-V - Peroxisomal antioxidant enzyme - TPx type VI - Thioredoxin peroxidase PMP20
Gene names	PRDX5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P30044

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Cytoplasmic+peroxisomal of Peroxiredoxin-5, mitochondrial - Isoform 3 of Peroxiredoxin-5, mitochondrial - Isoform 4 of Peroxiredoxin-5, mitochondrial

Sequence View

        10         20         30         40         50         60
MGLAGVCALR RSAGYILVGG AGGQSAAAAA RRYSEGEWAS GGVRSFSRAA AAMAPIKVGD
        70         80         90        100        110        120
AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV
       130        140        150        160        170        180
QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR
       190        200        210
FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL         10         20         30         40         50         60
MGLAGVCALR RSAGYILVGG AGGQSAAAAA RRYSEGEWAS GGVRSFSRAA AAMAPIKVGD
        70         80         90        100        110        120
AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV
       130        140        150        160        170        180
QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR
       190        200        210
FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL         10         20         30         40         50         60
MGLAGVCALR RSAGYILVGG AGGQSAAAAA RRYSEGEWAS GGVRSFSRAA AAMAPIKVGD
        70         80         90        100        110        120
AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV
       130        140        150        160        170        180
QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR
       190        200        210
FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P30044-1-unknown	MGLAGV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86152
P30044-1-unknown	MGLAGV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86153
P30044-53-unknown	MAPIKV...	53	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30044-53-unknown	MAPIKV...	53	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86151
P30044-53-unknown	MAPIKV...	53	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103561
P30044-54-	APIKVG...	54		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P30044-54-	APIKVG...	54		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P30044-54-	APIKVG...	54		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P30044-54-	APIKVG...	54		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P30044-54-	APIKVG...	54		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P30044-54-unknown	APIKVG...	54	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167128
P30044-54-unknown	APIKVG...	54	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167127

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IISQL	214	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IISQL	214	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81771
...IISQL	214	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81769
...IISQL	214	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81770

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)