P31146: Coronin-1A

General Information

Protein names	- Coronin-1A - Coronin-like protein A - Clipin-A - Coronin-like protein p57 - Tryptophan aspartate-containing coat protein - TACO
Gene names	CORO1A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31146

9 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI CEASGGGAFL
        70         80         90        100        110        120
VLPLGKTGRV DKNAPTVCGH TAPVLDIAWC PHNDNVIASG SEDCTVMVWE IPDGGLMLPL
       130        140        150        160        170        180
REPVVTLEGH TKRVGIVAWH TTAQNVLLSA GCDNVIMVWD VGTGAAMLTL GPEVHPDTIY
       190        200        210        220        230        240
SVDWSRDGGL ICTSCRDKRV RIIEPRKGTV VAEKDRPHEG TRPVRAVFVS EGKILTTGFS
       250        260        270        280        290        300
RMSERQVALW DTKHLEEPLS LQELDTSSGV LLPFFDPDTN IVYLCGKGDS SIRYFEITSE
       310        320        330        340        350        360
APFLHYLSMF SSKESQRGMG YMPKRGLEVN KCEIARFYKL HERRCEPIAM TVPRKSDLFQ
       370        380        390        400        410        420
EDLYPPTAGP DPALTAEEWL GGRDAGPLLI SLKDGYVPPK SRELRVNRGL DTGRRRAAPE
       430        440        450        460
ASGTPSSDAV SRLEEEMRKL QATVQELQKR LDRLEETVQA K

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P31146-2-unknown	MSRQVV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P31146-2-Acetylation	SRQVVR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P31146-355-unknown	KSDLFQ...	355			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P31146-355-	KSDLFQ...	355			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P31146-355-	KSDLFQ...	355			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P31146-395-	GYVPPK...	395			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P31146-417-unknown	AAPEAS...	417			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P31146-417-	AAPEAS...	417			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P31146-423-unknown	GTPSSD...	423			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P31146-423-	GTPSSD...	423			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P31146-423-	GTPSSD...	423			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P31146-423-	GTPSSD...	423			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...QNVLLS	148	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454752
...VGTGAA	165	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457509
...TIYSVD	182	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456756
...RQVALW	249	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000456266
...YLCGKG	287	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457332
...TVQAK	461	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...TVQAK	461		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...TVQAK	461		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)