P31937: 3-hydroxyisobutyrate dehydrogenase, mitochondrial

General Information

Protein names	- 3-hydroxyisobutyrate dehydrogenase, mitochondrial - HIBADH - 1.1.1.31
Gene names	HIBADH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P31937

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASLRLLGA ASGLRYWSRR LRPAAGSFAA VCSRSVASKT PVGFIGLGNM GNPMAKNLMK
        70         80         90        100        110        120
HGYPLIIYDV FPDACKEFQD AGEQVVSSPA DVAEKADRII TMLPTSINAI EAYSGANGIL
       130        140        150        160        170        180
KKVKKGSLLI DSSTIDPAVS KELAKEVEKM GAVFMDAPVS GGVGAARSGN LTFMVGGVED
       190        200        210        220        230        240
EFAAAQELLG CMGSNVVYCG AVGTGQAAKI CNNMLLAISM IGTAEAMNLG IRLGLDPKLL
       250        260        270        280        290        300
AKILNMSSGR CWSSDTYNPV PGVMDGVPSA NNYQGGFGTT LMAKDLGLAQ DSATSTKSPI
       310        320        330
LLGSLAHQIY RMMCAKGYSK KDFSSVFQFL REEETF

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P31937-36-	VASKTP...	36		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P31937-36-	VASKTP...	36		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P31937-37-unknown	ASKTPV...	37	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P31937-37-	ASKTPV...	37		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PVPGVM	263	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000390205
	...EEETF	336	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)