P34152: Focal adhesion kinase 1

General Information

Protein names	- Focal adhesion kinase 1 - FADK 1 - 2.7.10.2 - Focal adhesion kinase-related nonkinase - FRNK - Protein-tyrosine kinase 2 - p125FAK - pp125FAK
Gene names	Ptk2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P34152

5 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Focal adhesion kinase 1 - Isoform 3 of Focal adhesion kinase 1 - Isoform 4 of Focal adhesion kinase 1 - Isoform 5 of Focal adhesion kinase 1 - Isoform 6 of Focal adhesion kinase 1 - Isoform 7 of Focal adhesion kinase 1 - Isoform 8 of Focal adhesion kinase 1 - Isoform 9 of Focal adhesion kinase 1

Sequence View

        10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH         10         20         30         40         50         60
MAAAYLDPNL NHTPSSSTKT HLGTGMERSP GAMERVLKVF HYFESSSEPT TWASIIRHGD
        70         80         90        100        110        120
ATDVRGIIQK IVDSHKVKHV ACYGFRLSHL RSEEVHWLHV DMGVSSVREK YELAHPPEEW
       130        140        150        160        170        180
KYELRIRYLP KGFLNQFTED KPTLNFFYQQ VKSDYMQEIA DQVDQEIALK LGCLEIRRSY
       190        200        210        220        230        240
WEMRGNALEK KSNYEVLEKD VGLKRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI
       250        260        270        280        290        300
LKFFEILSPV YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGCNP THLADFNQVQ
       310        320        330        340        350        360
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL VNGATQSFII
       370        380        390        400        410        420
RPQKEGERAL PSIPKLANSE KQGMRTHAVS VSETDDYAEI IDEEDTYTMP STRDYEIQRE
       430        440        450        460        470        480
RIELGRCIGE GQFGDVHQGV YLSPENPALA VAIKTCKNCT SDSVREKFLQ EALTMRQFDH
       490        500        510        520        530        540
PHIVKLIGVI TENPVWIIME LCTLGELRSF LQVRKYSLDL ASLILYAYQL STALAYLESK
       550        560        570        580        590        600
RFVHRDIAAR NVLVSSNDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
       610        620        630        640        650        660
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT LYSLMTKCWA
       670        680        690        700        710        720
YDPSRRPRFT ELKAQLSTIL EEEKVQQEER MRMESRRQAT VSWDSGGSDE APPKPSRPGY
       730        740        750        760        770        780
PSPRSSEGFY PSPQHMVQTN HYQVSGYPGS HGIPAMAGSI YQGQASLLDQ TELWNHRPQE
       790        800        810        820        830        840
MSMWQPSVED SAALDLRGMG QVLPPHLMEE RLIRQQQEME EDQRWLEKEE RFLKPDVRLS
       850        860        870        880        890        900
RGSIDREDGS FQGPTGNQHI YQPVGKPDPA APPKKPPRPG APGHLSNLSS ISSPADSYNE
       910        920        930        940        950        960
GVKLQPQEIS PPPTANLDRS NDKVYENVTG LVKAVIEMSS KIQPAPPEEY VPMVKEVGLA
       970        980        990       1000       1010       1020
LRTLLATVDE TIPALPASTH REIEMAQKLL NSDLGELISK MKLAQQYVMT SLQQEYKKQM
      1030       1040       1050
LTAAHALAVD AKNLLDVIDQ ARLKMLGQTR PH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P34152-2-unknown	MAAAYL...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74744
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74745
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74746
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74747
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74748
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74749
P34152-1-unknown	MAAAYL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74750
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110312
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110313
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110314
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110315
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110316
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110317
P34152-2-Acetylation	AAAYLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110318
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74751
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109966
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109968
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109969
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109970
P34152-731-unknown	PSPQHM...	731		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109967
P34152-784-unknown	WQPSVE...	784		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28327
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139470
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156249
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156250
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156251
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156417
P34152-784-unknown	WQPSVE...	784		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156448

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70368
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91919
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91920
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91921
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91922
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91923
...YEVLEK	198	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91924
...QEMSMW	783	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28327
...QEMSMW	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122560
...	1090	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...	1090	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70369
...	1090	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70363
...	1090	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70364
...	1090	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70362

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CAN2_MOUSE	783	MSMW.\|.WQPS	inferred from experiment	unknown	MEROPS	Huttenlocher A	Chan KT et al.:Regulation of adhesion dynamics... (C02.002)	20150423,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)