P49722: Proteasome subunit alpha type-2

General Information

Protein names	- Proteasome subunit alpha type-2 - 3.4.25.1 {ECO:0000250\|UniProtKB:P25787} - Macropain subunit C3 - Multicatalytic endopeptidase complex subunit C3 - Proteasome component C3
Gene names	Psma2
Organism	Mus musculus
Protease Family
Protease ID	T01.972
Chromosome location
UniProt ID	P49722

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAERGYSFSL TTFSPSGKLV QIEYALAAVA GGAPSVGIKA ANGVVLATEK KQKSILYDER
        70         80         90        100        110        120
SVHKVEPITK HIGLVYSGMG PDYRVLVHRA RKLAQQYYLV YQEPIPTAQL VQRVASVMQE
       130        140        150        160        170        180
YTQSGGVRPF GVSLLICGWN EGRPYLFQSD PSGAYFAWKA TAMGKNYVNG KTFLEKRYNE
       190        200        210        220        230
DLELEDAIHT AILTLKESFE GQMTEDNIEV GICNEAGFRR LTPTEVRDYL AAIA

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P49722-2-unknown	MAERGY...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P49722-2-Acetylation	AERGYS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P49722-47-unknown	ATEKKQ...	47		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30018
P49722-47-unknown	ATEKKQ...	47		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28897
P49722-75-unknown	VYSGMG...	75		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33590
P49722-98-unknown	YLVYQE...	98		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30019

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NGVVLA	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30018
...NGVVLA	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28897
...KHIGLV	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33590
...LAQQYY	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30019
...LAAIA	234	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	46	VVLA.\|.ATEK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA2_MOUSE @46
CATD_MOUSE	46	VVLA.\|.ATEK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PSA2_MOUSE @46
MMP2_MOUSE	74	IGLV.\|.VYSG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	97	QQYY.\|.YLVY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA2_MOUSE @97

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)