P52594: Arf-GAP domain and FG repeat-containing protein 1
Protein names | - Arf-GAP domain and FG repeat-containing protein 1 - HIV-1 Rev-binding protein - Nucleoporin-like protein RIP - Rev-interacting protein - Rev/Rex activation domain-binding protein |
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Gene names | AGFG1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P52594 |
10
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN
70 80 90 100 110 120
PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK
130 140 150 160 170 180
YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ
190 200 210 220 230 240
SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF
250 260 270 280 290 300
ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN
310 320 330 340 350 360
TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV
370 380 390 400 410 420
VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS
430 440 450 460 470 480
SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY
490 500 510 520 530 540
SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN
550 560
PFMTGAPTGQ FPTGSSSTNP FL
Isoforms
- Isoform 2 of Arf-GAP domain and FG repeat-containing protein 1 - Isoform 3 of Arf-GAP domain and FG repeat-containing protein 1 - Isoform 4 of Arf-GAP domain and FG repeat-containing protein 1 - Isoform 4 of Arf-GAP domain and FG repeat-containing protein 1Sequence View
10 20 30 40 50 60
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN
70 80 90 100 110 120
PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK
130 140 150 160 170 180
YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ
190 200 210 220 230 240
SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF
250 260 270 280 290 300
ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN
310 320 330 340 350 360
TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV
370 380 390 400 410 420
VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS
430 440 450 460 470 480
SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY
490 500 510 520 530 540
SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN
550 560
PFMTGAPTGQ FPTGSSSTNP FL
10 20 30 40 50 60
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN
70 80 90 100 110 120
PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK
130 140 150 160 170 180
YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ
190 200 210 220 230 240
SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF
250 260 270 280 290 300
ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN
310 320 330 340 350 360
TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV
370 380 390 400 410 420
VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS
430 440 450 460 470 480
SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY
490 500 510 520 530 540
SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN
550 560
PFMTGAPTGQ FPTGSSSTNP FL
10 20 30 40 50 60
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN
70 80 90 100 110 120
PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK
130 140 150 160 170 180
YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ
190 200 210 220 230 240
SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF
250 260 270 280 290 300
ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN
310 320 330 340 350 360
TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV
370 380 390 400 410 420
VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS
430 440 450 460 470 480
SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY
490 500 510 520 530 540
SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN
550 560
PFMTGAPTGQ FPTGSSSTNP FL
10 20 30 40 50 60
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN
70 80 90 100 110 120
PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK
130 140 150 160 170 180
YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ
190 200 210 220 230 240
SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF
250 260 270 280 290 300
ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN
310 320 330 340 350 360
TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV
370 380 390 400 410 420
VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS
430 440 450 460 470 480
SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY
490 500 510 520 530 540
SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN
550 560
PFMTGAPTGQ FPTGSSSTNP FL
Protein Neighborhood
Domains & Features
10 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P52594-1-unknown | MAASAK... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P52594-1-unknown | MAASAK... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt66499 | |||
P52594-1-unknown | MAASAK... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt66500 | |||
P52594-16-unknown | MLRDMT... | 16 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt66501 | |||
P52594-16-unknown | MLRDMT... | 16 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106896 | |||
P52594-16-unknown | MLRDMT... | 16 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106897 | |||
P52594-141- | ASISGS... | 141 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P52594-141-unknown | ASISGS... | 141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175576 | |||
P52594-141-unknown | ASISGS... | 141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175577 | |||
P52594-141-unknown | ASISGS... | 141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175578 | |||
P52594-145- | GSSASS... | 145 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P52594-145- | GSSASS... | 145 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P52594-145- | GSSASS... | 145 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P52594-145- | GSSASS... | 145 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P52594-145-unknown | GSSASS... | 145 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5998 | |||
P52594-145-unknown | GSSASS... | 145 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt143896 | |||
P52594-145-unknown | GSSASS... | 145 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144528 | |||
P52594-145-unknown | GSSASS... | 145 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144529 | |||
P52594-146-unknown | SSASST... | 146 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175572 | |||
P52594-146-unknown | SSASST... | 146 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175573 | |||
P52594-146-unknown | SSASST... | 146 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175574 | |||
P52594-146- | SSASST... | 146 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P52594-153- | STPEVK... | 153 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P52594-153-unknown | STPEVK... | 153 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167682 | |||
P52594-153-unknown | STPEVK... | 153 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167683 | |||
P52594-153-unknown | STPEVK... | 153 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167684 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...HASISG | 144 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5998 | |||
...HASISG | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127140 | |||
...HASISG | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127795 | |||
...HASISG | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127796 | |||
...TNPFL | 562 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...TNPFL | 562 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt62117 | |||
...TNPFL | 562 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt62118 | |||
...TNPFL | 562 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt62119 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 144 | SISG.|.GSSA | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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