P53708: Integrin alpha-8
Protein names | - Integrin alpha-8 - Integrin alpha-8 heavy chain - Integrin alpha-8 light chain |
---|---|
Gene names | ITGA8 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P53708 |
2
N-termini
2
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSPGASRGPR GSQAPLIAPL CCAAAALGML LWSPACQAFN LDVEKLTVYS GPKGSYFGYA
70 80 90 100 110 120
VDFHIPDART ASVLVGAPKA NTSQPDIVEG GAVYYCPWPA EGSAQCRQIP FDTTNNRKIR
130 140 150 160 170 180
VNGTKEPIEF KSNQWFGATV KAHKGKVVAC APLYHWRTLK PTPEKDPVGT CYVAIQNFSA
190 200 210 220 230 240
YAEFSPCRNS NADPEGQGYC QAGFSLDFYK NGDLIVGGPG SFYWQGQVIT ASVADIIANY
250 260 270 280 290 300
SFKDILRKLA GEKQTEVAPA SYDDSYLGYS VAAGEFTGDS QQELVAGIPR GAQNFGYVSI
310 320 330 340 350 360
INSTDMTFIQ NFTGEQMASY FGYTVVVSDV NSDGLDDVLV GAPLFMEREF ESNPREVGQI
370 380 390 400 410 420
YLYLQVSSLL FRDPQILTGT ETFGRFGSAM AHLGDLNQDG YNDIAIGVPF AGKDQRGKVL
430 440 450 460 470 480
IYNGNKDGLN TKPSQVLQGV WASHAVPSGF GFTLRGDSDI DKNDYPDLIV GAFGTGKVAV
490 500 510 520 530 540
YRARPVVTVD AQLLLHPMII NLENKTCQVP DSMTSAACFS LRVCASVTGQ SIANTIVLMA
550 560 570 580 590 600
EVQLDSLKQK GAIKRTLFLD NHQAHRVFPL VIKRQKSHQC QDFIVYLRDE TEFRDKLSPI
610 620 630 640 650 660
NISLNYSLDE STFKEGLEVK PILNYYRENI VSEQAHILVD CGEDNLCVPD LKLSARPDKH
670 680 690 700 710 720
QVIIGDENHL MLIINARNEG EGAYEAELFV MIPEEADYVG IERNNKGFRP LSCEYKMENV
730 740 750 760 770 780
TRMVVCDLGN PMVSGTNYSL GLRFAVPRLE KTNMSINFDL QIRSSNKDNP DSNFVSLQIN
790 800 810 820 830 840
ITAVAQVEIR GVSHPPQIVL PIHNWEPEEE PHKEEEVGPL VEHIYELHNI GPSTISDTIL
850 860 870 880 890 900
EVGWPFSARD EFLLYIFHIQ TLGPLQCQPN PNINPQDIKP AASPEDTPEL SAFLRNSTIP
910 920 930 940 950 960
HLVRKRDVHV VEFHRQSPAK ILNCTNIECL QISCAVGRLE GGESAVLKVR SRLWAHTFLQ
970 980 990 1000 1010 1020
RKNDPYALAS LVSFEVKKMP YTDQPAKLPE GSIVIKTSVI WATPNVSFSI PLWVIILAIL
1030 1040 1050 1060
LGLLVLAILT LALWKCGFFD RARPPQEDMT DREQLTNDKT PEA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 4 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P53708-39-unknown | FNLDVE... | 39 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P53708-907-unknown | DVHVVE... | 907 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P53708-907-unknown | DVHVVE... | 907 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26897 | |||
P53708-907-unknown | DVHVVE... | 907 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27195 | |||
P53708-907-unknown | DVHVVE... | 907 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27045 | |||
P53708-907-unknown | DVHVVE... | 907 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27342 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LVRKRD | 906 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...LVRKRD | 906 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC26897 | |||
...LVRKRD | 906 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27195 | |||
...LVRKRD | 906 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27045 | |||
...LVRKRD | 906 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27342 | |||
...KTPEA | 1063 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
PCSK4_HUMAN | 906 | RKRD.|.DVHV | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK6_HUMAN | 906 | RKRD.|.DVHV | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK5_HUMAN | 906 | RKRD.|.DVHV | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
PCSK7_HUMAN | 906 | RKRD.|.DVHV | inferred from experiment | unknown | MEROPS | Strongin AY | Remacle AG et al.:Substrate cleavage analysis of ... (S08.071) | 18505722, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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