P61163: Alpha-centractin

General Information

Protein names	- Alpha-centractin - Centractin - ARP1 - Actin-RPV - Centrosome-associated actin homolog
Gene names	ACTR1A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P61163

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESYDVIANQ PVVIDNGSGV IKAGFAGDQI PKYCFPNYVG RPKHVRVMAG ALEGDIFIGP
        70         80         90        100        110        120
KAEEHRGLLS IRYPMEHGIV KDWNDMERIW QYVYSKDQLQ TFSEEHPVLL TEAPLNPRKN
       130        140        150        160        170        180
RERAAEVFFE TFNVPALFIS MQAVLSLYAT GRTTGVVLDS GDGVTHAVPI YEGFAMPHSI
       190        200        210        220        230        240
MRIDIAGRDV SRFLRLYLRK EGYDFHSSSE FEIVKAIKER ACYLSINPQK DETLETEKAQ
       250        260        270        280        290        300
YYLPDGSTIE IGPSRFRAPE LLFRPDLIGE ESEGIHEVLV FAIQKSDMDL RRTLFSNIVL
       310        320        330        340        350        360
SGGSTLFKGF GDRLLSEVKK LAPKDVKIRI SAPQERLYST WIGGSILASL DTFKKMWVSK
       370
KEYEEDGARS IHRKTF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P61163-1-Acetylation	MESYDV...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P61163-1-Acetylation	MESYDV...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P61163-48-unknown	MAGALE...	48		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406028
P61163-75-unknown	MEHGIV...	75		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000438890
P61163-106-unknown	HPVLLT...	106		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19237
P61163-207-unknown	SSSEFE...	207		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6078
P61163-264-unknown	RPDLIG...	264		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6079

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TFSEEH	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19237
...GYDFHS	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6078
...PELLFR	263	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6079
...HRKTF	376	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	105	SEEH.\|.HPVL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	206	DFHS.\|.SSSE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	263	LLFR.\|.RPDL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)