P63089: Pleiotrophin {ECO:0000250|UniProtKB:P21246}
| Protein names | - Pleiotrophin {ECO:0000250|UniProtKB:P21246} - PTN {ECO:0000250|UniProtKB:P21246} - Heparin-binding brain mitogen {ECO:0000250|UniProtKB:P21246} - HBBM {ECO:0000250|UniProtKB:P21246} - Heparin-binding growth factor 8 {ECO:0000250|UniProtKB:P21782} - HBGF-8 {ECO:0000250|UniProtKB:P21782} - Heparin-binding growth-associated molecule {ECO:0000250|UniProtKB:P63090} - HB-GAM {ECO:0000250|UniProtKB:P63090} - Heparin-binding neutrophic factor {ECO:0000250|UniProtKB:P21246} - HBNF {ECO:0000250|UniProtKB:P21246} - Osteoblast-specific factor 1 {ECO:0000303|PubMed:1701634} - OSF-1 {ECO:0000303|PubMed:1701634} |
|---|---|
| Gene names | Ptn |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P63089 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSSQQYQQQR RKFAAAFLAL IFILAAVDTA EAGKKEKPEK KVKKSDCGEW QWSVCVPTSG
70 80 90 100 110 120
DCGLGTREGT RTGAECKQTM KTQRCKIPCN WKKQFGAECK YQFQAWGECD LNTALKTRTG
130 140 150 160
SLKRALHNAD CQKTVTISKP CGKLTKPKPQ AESKKKKKEG KKQEKMLD
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P63089-33-unknown | GKKEKP... | 33 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P63089-91-unknown | WKKQFG... | 91 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33739 | |||
| P63089-104-Pyrrolidone carboxylic acid | QAWGEC... | 104 | pyrrolidone carboxylic acid- | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | ||
| P63089-150-unknown | QAESKK... | 150 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33740 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...KIPCNW | 90 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33739 | |||
| ...TKPKPQ | 149 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33740 | |||
| ...EKMLD | 168 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP2_MOUSE | 90 | PCNW.|.WKKQ | inferred from experiment | unknown | MEROPS | Overall CM | Dean RA et al.:Identification of candidate ang... (M10.003) | 17908800, |
| MMP2_MOUSE | 149 | PKPQ.|.QAES | inferred from experiment | unknown | MEROPS | Overall CM | Dean RA et al.:Identification of candidate ang... (M10.003) | 17908800, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|