P68402: Platelet-activating factor acetylhydrolase IB subunit beta

General Information

Protein names	- Platelet-activating factor acetylhydrolase IB subunit beta - 3.1.1.47 - PAF acetylhydrolase 30 kDa subunit - PAF-AH 30 kDa subunit - PAF-AH subunit beta - PAFAH subunit beta
Gene names	PAFAH1B2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P68402

8 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Platelet-activating factor acetylhydrolase IB subunit beta - Isoform 3 of Platelet-activating factor acetylhydrolase IB subunit beta - Isoform 4 of Platelet-activating factor acetylhydrolase IB subunit beta

Sequence View

        10         20         30         40         50         60
MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR
        70         80         90        100        110        120
ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA
       130        140        150        160        170        180
IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDTDGGFV
       190        200        210        220
HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA         10         20         30         40         50         60
MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR
        70         80         90        100        110        120
ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA
       130        140        150        160        170        180
IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDTDGGFV
       190        200        210        220
HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA         10         20         30         40         50         60
MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR
        70         80         90        100        110        120
ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA
       130        140        150        160        170        180
IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDTDGGFV
       190        200        210        220
HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P68402-1-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84114
P68402-1-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84115
P68402-1-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84116
P68402-2-unknown	MSQGDS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P68402-2-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164441
P68402-2-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164442
P68402-2-unknown	MSQGDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164443
P68402-2-	SQGDSN...	2			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P68402-2-	SQGDSN...	2			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P68402-2-	SQGDSN...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P68402-2-	SQGDSN...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P68402-2-	SQGDSN...	2			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P68402-2-Acetylation	SQGDSN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P68402-2-Acetylation	SQGDSN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P68402-2-Acetylation	SQGDSN...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P68402-2-Acetylation	SQGDSN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P68402-2-Acetylation	SQGDSN...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P68402-2-Acetylation	SQGDSN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111582
P68402-2-Acetylation	SQGDSN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111583
P68402-2-Acetylation	SQGDSN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111584
P68402-6-	SNPAAI...	6			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P68402-6-unknown	SNPAAI...	6		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175902
P68402-6-unknown	SNPAAI...	6		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175903
P68402-6-unknown	SNPAAI...	6		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175904
P68402-61-	ELFSPL...	61			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P68402-61-unknown	ELFSPL...	61		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182867
P68402-61-unknown	ELFSPL...	61		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182868
P68402-61-unknown	ELFSPL...	61		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt182869

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RQPQAK	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79733
...RQPQAK	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91625
...RQPQAK	132	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91626
...QTTIA	229	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)