P70349: Histidine triad nucleotide-binding protein 1

General Information

Protein names	- Histidine triad nucleotide-binding protein 1 - 3.-.-.- - Adenosine 5'-monophosphoramidase - Protein kinase C inhibitor 1 - Protein kinase C-interacting protein 1 - PKCI-1
Gene names	Hint1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P70349

8 N-termini

7 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADEIAKAQV AQPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI
        70         80         90        100        110        120
SQISVADDDD ESLLGHLMIV GKKCAADLGL KRGYRMVVNE GADGGQSVYH IHLHVLGGRQ

MNWPPG

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
P70349-2-unknown	MADEIA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P70349-2-unknown	MADEIA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70349-2-Acetylation	ADEIAK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70349-2-Acetylation	ADEIAK...	2	acetylation-		unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P70349-2-Acetylation	ADEIAK...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P70349-9-unknown	QVAQPG...	9		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33800
P70349-10-unknown	VAQPGG...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30328
P70349-31-unknown	IIFEDD...	31		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33801
P70349-31-unknown	IIFEDD...	31		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70349-31-unknown	IIFEDD...	31		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P70349-63-unknown	ISVADD...	63		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33802
P70349-78-unknown	MIVGKK...	78		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29073
P70349-82-unknown	KKCAAD...	82		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29074

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EIAKAQ	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33800
...IAKAQV	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30328
...EIPAKI	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33801
...KHISQI	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33802
...LLGHLM	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29073
...LMIVGK	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29074
...NWPPG	126	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	8	AKAQ.\|.QVAQ	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> HINT1_MOUSE @8
CATE_MOUSE	9	KAQV.\|.VAQP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> HINT1_MOUSE @9
MMP2_MOUSE	30	PAKI.\|.IIFE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	62	ISQI.\|.ISVA	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> HINT1_MOUSE @62
CATD_MOUSE	77	GHLM.\|.MIVG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> HINT1_MOUSE @77
CATD_MOUSE	81	IVGK.\|.KKCA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> HINT1_MOUSE @81

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)