P80317: T-complex protein 1 subunit zeta

General Information

Protein names	- T-complex protein 1 subunit zeta - TCP-1-zeta - CCT-zeta-1
Gene names	Cct6a
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P80317

8 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVKTLNPK AEVARAQAAL AVNISAARGL QDVLRTNLGP KGTMKMLVSG AGDIKLTKDG
        70         80         90        100        110        120
NVLLHEMQIQ HPTASLIAKV ATAQDDITGD GTTSNVLIIG ELLKQADLYI SEGLHPRIIT
       130        140        150        160        170        180
EGFEAAKEKA LQFLEQVKVS KEMDRETLID VARTSLRTKV HAELADVLTE AVVDSILAIR
       190        200        210        220        230        240
KKDEPIDLFM VEIMEMKHKS ETDTSLIRGL VLDHGARHPD MKKRVENAYI LTCNVSLEYE
       250        260        270        280        290        300
KTEVNSGFFY KSAEEREKLV KAERKFIEDR VKKIIELKKK VCGDSDKGFV VINQKGIDPF
       310        320        330        340        350        360
SLDALAKEGI VALRRAKRRN MERLTLACGG IALNSFDDLN PDCLGHAGLV YEYTLGEEKF
       370        380        390        400        410        420
TFIEKCNNPR SVTLLVKGPN KHTLTQIKDA IRDGLRAVKN AIDDGCVVPG AGAVEVALAE
       430        440        450        460        470        480
ALIKYKPSVK GRAQLGVQAF ADALLIIPKV LAQNSGFDLQ ETLVKVQAEH SESGQLVGVD
       490        500        510        520        530
LSTGEPMVAA EMGVWDNYCV KKQLLHSCTV IATNILLVDE IMRAGMSSLK G

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80317-2-unknown	MAAVKT...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80317-2-unknown	MAAVKT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80317-2-Acetylation	AAVKTL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80317-2-Acetylation	AAVKTL...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P80317-2-Acetylation	AAVKTL...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P80317-2-Acetylation	AAVKTL...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P80317-21-unknown	AVNISA...	21		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30346
P80317-102-unknown	LLKQAD...	102		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33816
P80317-108-unknown	LYISEG...	108		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33817
P80317-209-unmodified	GLVLDH...	209			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P80317-210-unknown	LVLDHG...	210		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33818
P80317-303-unknown	DALAKE...	303		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30347

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AQAALA	20	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30346
...LIIGEL	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33816
...LKQADL	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33817
...SLIRGL	209	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33818
...DPFSLD	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30347
...SSLKG	531	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	20	AALA.\|.AVNI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPZ_MOUSE @20
MMP2_MOUSE	101	IGEL.\|.LLKQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	107	QADL.\|.LYIS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	209	IRGL.\|.LVLD	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATE_MOUSE	302	FSLD.\|.DALA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TCPZ_MOUSE @302

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)