P97855: Ras GTPase-activating protein-binding protein 1

General Information

Protein names	- Ras GTPase-activating protein-binding protein 1 - G3BP-1 - 3.6.4.12 {ECO:0000250\|UniProtKB:Q13283} - 3.6.4.13 {ECO:0000250\|UniProtKB:Q13283} - ATP-dependent DNA helicase VIII - GAP SH3 domain-binding protein 1 - HDH-VIII
Gene names	G3bp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P97855

5 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY AHGGLDSNGK PADAVYGQKE
        70         80         90        100        110        120
IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN NNQALRRFMQ TFVLAPEGSV
       130        140        150        160        170        180
ANKFYVHNDI FRYQDEVFGG FVTEPQEESE EEVEEPEERQ QTPEVVPDDS GTFYDQTVSN
       190        200        210        220        230        240
DLEEHLEEPV VEPEPEPEPE PEPEPVSDIQ EDKPEAALEE AAPDDVQKST SPAPADVAPA
       250        260        270        280        290        300
QEDLRTFSWA SVTSKNLPPS GAVPVTGTPP HVVKVPASQP RPESKPDSQI PPQRPQRDQR
       310        320        330        340        350        360
VREQRINIPP QRGPRPIREA GEPGDVEPRR MVRHPDSHQL FIGNLPHEVD KSELKDFFQN
       370        380        390        400        410        420
FGNVVELRIN SGGKLPNFGF VVFDDSEPVQ KVLSNRPIMF RGAVRLNVEE KKTRAAREGD
       430        440        450        460
RRDNRLRGPG GPRGGPSGGM RGPPRGGMVQ KPGFGVGRGI TTPRQ

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P97855-2-unknown	VMEKPS...	2	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P97855-2-unknown	VMEKPS...	2	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P97855-19-unknown	YYTLLN...	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33828
P97855-119-unknown	SVANKF...	119	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33829
P97855-123-unknown	KFYVHN...	123	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33830
P97855-407-unknown	NVEEKK...	407	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29108

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EFVRQY	18	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33828
...LAPEGS	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33829
...GSVANK	122	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33830
...GAVRLN	406	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29108
...TTPRQ	465	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	18	VRQY.\|.YYTL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	118	PEGS.\|.SVAN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	122	VANK.\|.KFYV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	406	VRLN.\|.NVEE	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)