Q00577: Transcriptional activator protein Pur-alpha

General Information

Protein names	- Transcriptional activator protein Pur-alpha - Purine-rich single-stranded DNA-binding protein alpha
Gene names	PURA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q00577

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA PGGLQHETQE
        70         80         90        100        110        120
LASKRVDIQN KRFYLDVKQN AKGRFLKIAE VGAGGNKSRL TLSMSVAVEF RDYLGDFIEH
       130        140        150        160        170        180
YAQLGPSQPP DLAQAQDEPR RALKSEFLVR ENRKYYMDLK ENQRGRFLRI RQTVNRGPGL
       190        200        210        220        230        240
GSTQGQTIAL PAQGLIEFRD ALAKLIDDYG VEEEPAELPE GTSLTVDNKR FFFDVGSNKY
       250        260        270        280        290        300
GVFMRVSEVK PTYRNSITVP YKVWAKFGHT FCKYSEEMKK IQEKQREKRA ACEQLHQQQQ
       310        320
QQQEETAAAT LLLQGEEEGE ED

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q00577-1-unknown	MADRDS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q00577-43-	SGGGGG...	43		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q00577-52-	GGLQHE...	52		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q00577-56-unknown	HETQEL...	56	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6189

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PGGLQH	55	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6189
	...EGEED	322	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	55	GLQH.\|.HETQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)