Q02053: Ubiquitin-like modifier-activating enzyme 1
Protein names | - Ubiquitin-like modifier-activating enzyme 1 - 6.2.1.45 {ECO:0000250|UniProtKB:P22314} - Ubiquitin-activating enzyme E1 - Ubiquitin-activating enzyme E1 X - Ubiquitin-like modifier-activating enzyme 1 X |
---|---|
Gene names | Uba1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q02053 |
16
N-termini
10
C-termini
10
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSSSPLSKKR RVSGPDPKPG SNCSPAQSAL SEVSSVPTNG MAKNGSEADI DESLYSRQLY
70 80 90 100 110 120
VLGHEAMKML QTSSVLVSGL RGLGVEIAKN IILGGVKAVT LHDQGTTQWA DLSSQFYLRE
130 140 150 160 170 180
EDIGKNRAEV SQPRLAELNS YVPVTAYTGP LVEDFLSSFQ VVVLTNSPLE AQLRVGEFCH
190 200 210 220 230 240
SRGIKLVVAD TRGLFGQLFC DFGEEMVLTD SNGEQPLSAM VSMVTKDNPG VVTCLDEARH
250 260 270 280 290 300
GFETGDFVSF SEVQGMIQLN GCQPMEIKVL GPYTFSICDT SNFSDYIRGG IVSQVKVPKK
310 320 330 340 350 360
ISFKSLPASL VEPDFVMTDF AKYSRPAQLH IGFQALHQFC ALHNQPPRPR NEEDATELVG
370 380 390 400 410 420
LAQAVNARSP PSVKQNSLDE DLIRKLAYVA AGDLAPINAF IGGLAAQEVM KACSGKFMPI
430 440 450 460 470 480
MQWLYFDALE CLPEDKEALT EEKCLPRQNR YDGQVAVFGS DFQEKLSKQK YFLVGAGAIG
490 500 510 520 530 540
CELLKNFAMI GLGCGEGGEV VVTDMDTIEK SNLNRQFLFR PWDVTKLKSD TAAAAVRQMN
550 560 570 580 590 600
PYIQVTSHQN RVGPDTERIY DDDFFQNLDG VANALDNIDA RMYMDRRCVY YRKPLLESGT
610 620 630 640 650 660
LGTKGNVQVV IPFLTESYSS SQDPPEKSIP ICTLKNFPNA IEHTLQWARD EFEGLFKQPA
670 680 690 700 710 720
ENVNQYLTDS KFVERTLRLA GTQPLEVLEA VQRSLVLQRP QTWGDCVTWA CHHWHTQYCN
730 740 750 760 770 780
NIRQLLHNFP PDQLTSSGAP FWSGPKRCPH PLTFDVNNTL HLDYVMAAAN LFAQTYGLTG
790 800 810 820 830 840
SQDRAAVASL LQSVQVPEFT PKSGVKIHVS DQELQSANAS VDDSRLEELK ATLPSPDKLP
850 860 870 880 890 900
GFKMYPIDFE KDDDSNFHMD FIVAASNLRA ENYDISPADR HKSKLIAGKI IPAIATTTAA
910 920 930 940 950 960
VVGLVCLELY KVVQGHQQLD SYKNGFLNLA LPFFGFSEPL AAPRHQYYNQ EWTLWDRFEV
970 980 990 1000 1010 1020
QGLQPNGEEM TLKQFLDYFK TEHKLEITML SQGVSMLYSF FMPAAKLKER LDQPMTEIVS
1030 1040 1050
RVSKRKLGRH VRALVLELCC NDESGEDVEV PYVRYTIR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
16 N-termini - 10 C-termini - 10 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q02053-2-unknown | MSSSPL... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q02053-2-unknown | MSSSPL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q02053-2-Acetylation | SSSPLS... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q02053-2-Acetylation | SSSPLS... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q02053-64-unmodified | HEAMKM... | 64 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
Q02053-220-unknown | MVSMVT... | 220 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33875 | |||
Q02053-223-unknown | MVTKDN... | 223 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33876 | |||
Q02053-224-unknown | VTKDNP... | 224 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33877 | |||
Q02053-225-unmodified | TKDNPG... | 225 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
Q02053-310-unknown | LVEPDF... | 310 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33878 | |||
Q02053-316-unknown | VMTDFA... | 316 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30395 | |||
Q02053-318-unknown | TDFAKY... | 318 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30396 | |||
Q02053-321-unknown | AKYSRP... | 321 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q02053-359-unknown | VGLAQA... | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29117 | |||
Q02053-359-unknown | VGLAQA... | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30397 | |||
Q02053-425-unmodified | YFDALE... | 425 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
Q02053-772-unknown | FAQTYG... | 772 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30398 | |||
Q02053-933-unknown | FFGFSE... | 933 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33879 | |||
Q02053-947-unmodified | YYNQEW... | 947 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QPLSAM | 219 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33875 | |||
...SAMVSM | 222 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33876 | |||
...AMVSMV | 223 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33877 | |||
...SLPASL | 309 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33878 | |||
...VEPDFV | 315 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30395 | |||
...PDFVMT | 317 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30396 | |||
...DATELV | 358 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29117 | |||
...DATELV | 358 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30397 | |||
...AAANLF | 771 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30398 | |||
...NLALPF | 932 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33879 | |||
...RYTIR | 1058 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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