Q02819: Nucleobindin-1

General Information

Protein names	- Nucleobindin-1 - CALNUC
Gene names	Nucb1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q02819

11 N-termini

10 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPTSVPRGAP FLLLPPLLML SAVLAVPVDR AAPPQEDSQA TETPDTGLYY HRYLQEVINV
        70         80         90        100        110        120
LETDGHFREK LQAANAEDIK SGKLSQELDF VSHNVRTKLD ELKRQEVSRL RMLLKAKMDA
       130        140        150        160        170        180
KQEPNLQVDH MNLLKQFEHL DPQNQHTFEA RDLELLIQTA TRDLAQYDAA HHEEFKRYEM
       190        200        210        220        230        240
LKEHERRRYL ESLGEEQRKE AERKLQEQQR RHREHPKVNV PGSQAQLKEV WEELDGLDPN
       250        260        270        280        290        300
RFNPKTFFIL HDINSDGVLD EQELEALFTK ELEKVYDPKN EEDDMREMEE ERLRMREHVM
       310        320        330        340        350        360
KNVDTNQDRL VTLEEFLAST QRKEFGDTGE GWKTVEMSPA YTEEELKRFE EELAAREAEL
       370        380        390        400        410        420
NARAQRLSQE TEALGRSQDR LEAQKRELQQ AVLQMEQRKQ QLQEQSAPPS KPDGQLQFRA
       430        440        450
DTDDAPVPAP AGDQKDVPAS EKKVPEQPPE LPQLDSQHL

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 10 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q02819-26-unknown	VPVDRA...	26	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q02819-54-unknown	LQEVIN...	54	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33881
Q02819-57-unknown	VINVLE...	57	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33882
Q02819-168-unmodified	DAAHHE...	168		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q02819-227-unknown	LKEVWE...	227	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33883
Q02819-230-unknown	VWEELD...	230	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33884
Q02819-334-unmodified	TVEMSP...	334		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q02819-334-unmodified	TVEMSP...	334		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q02819-367-unknown	LSQETE...	367	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33885
Q02819-388-unmodified	LQQAVL...	388		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q02819-388-unknown	LQQAVL...	388	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33886
Q02819-405-unknown	QSAPPS...	405	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33887

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YYHRYL	53	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33881
...RYLQEV	56	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33882
...KMDAKQ	121	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119703
...PKVNVP	220	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116036
...GSQAQL	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33883
...AQLKEV	229	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33884
...ARAQRL	366	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33885
...AQKREL	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33886
...KQQLQE	403	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135284
...KQQLQE	403	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33887
...DSQHL	459	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	53	HRYL.\|.LQEV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	56	LQEV.\|.VINV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	226	QAQL.\|.LKEV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	229	LKEV.\|.VWEE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	366	AQRL.\|.LSQE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	387	KREL.\|.LQQA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	404	LQEQ.\|.QSAP	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> NUCB1_MOUSE @404

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)