Q13404: Ubiquitin-conjugating enzyme E2 variant 1

General Information

Protein names	- Ubiquitin-conjugating enzyme E2 variant 1 - UEV-1 - CROC-1 - TRAF6-regulated IKK activator 1 beta Uev1A
Gene names	UBE2V1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13404

8 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Ubiquitin-conjugating enzyme E2 variant 1 - Isoform 2 of Ubiquitin-conjugating enzyme E2 variant 1 - Isoform 4 of Ubiquitin-conjugating enzyme E2 variant 1 - Isoform 5 of Ubiquitin-conjugating enzyme E2 variant 1 - Isoform 6 of Ubiquitin-conjugating enzyme E2 variant 1

Sequence View

        10         20         30         40         50         60
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
        70         80         90        100        110        120
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
       130        140
LQELRRLMMS KENMKLPQPP EGQCYSN         10         20         30         40         50         60
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
        70         80         90        100        110        120
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
       130        140
LQELRRLMMS KENMKLPQPP EGQCYSN         10         20         30         40         50         60
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
        70         80         90        100        110        120
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
       130        140
LQELRRLMMS KENMKLPQPP EGQCYSN         10         20         30         40         50         60
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
        70         80         90        100        110        120
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
       130        140
LQELRRLMMS KENMKLPQPP EGQCYSN         10         20         30         40         50         60
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
        70         80         90        100        110        120
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
       130        140
LQELRRLMMS KENMKLPQPP EGQCYSN

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13404-2-unknown	MAATTG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13404-1-unknown	MAATTG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93564
Q13404-2-Acetylation	AATTGS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13404-2-Acetylation	AATTGS...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13404-2-Acetylation	AATTGS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110219
Q13404-3-acetylation	ATTGSG...	3	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13404-3-acetylation	ATTGSG...	3	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183054
Q13404-36-unknown	GLEDDE...	36		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174055
Q13404-36-unknown	GLEDDE...	36		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174056
Q13404-36-unknown	GLEDDE...	36		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174057
Q13404-36-	GLEDDE...	36			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13404-127-	LMMSKE...	127			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q13404-127-unknown	LMMSKE...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164945
Q13404-127-unknown	LMMSKE...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164943
Q13404-127-unknown	LMMSKE...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164944
Q13404-127-unknown	LMMSKE...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164946

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...QCYSN	147	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QCYSN	147	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89180
...QCYSN	147	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89182
...QCYSN	147	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89179
...QCYSN	147	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89181
...	221		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)