TopFIND 4.0

Q14061: Cytochrome c oxidase copper chaperone

General Information

Protein names	- Cytochrome c oxidase copper chaperone
Gene names	COX17
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14061

6

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MPGLVDSNPA PPESQEKKPL KPCCACPETK KARDACIIEK GEEHCGHLIE AHKECMRALG

FKI

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14061-1-unknown	MPGLVD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14061-2-unmodified	PGLVDS...	2			other		CNRS/ISV	Large_scale_NTA_Human
Q14061-2-unknown	PGLVDS...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q14061-2-unknown	PGLVDS...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14061-3-	GLVDSN...	3			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q14061-3-	GLVDSN...	3			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q14061-3-	GLVDSN...	3			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14061-3-	GLVDSN...	3			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14061-3-	GLVDSN...	3			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14061-5-	VDSNPA...	5			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q14061-5-	VDSNPA...	5			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q14061-5-	VDSNPA...	5			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q14061-5-	VDSNPA...	5			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14061-5-	VDSNPA...	5			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q14061-43-unknown	EHCGHL...	43		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19491

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IEKGEE	42	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19491
	...LGFKI	63		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...LGFKI	63		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...LGFKI	63	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...LGFKI	63		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...LGFKI	63		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	42	KGEE.\|.EHCG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)