Q14696: LRP chaperone MESD {ECO:0000305}
Protein names | - LRP chaperone MESD {ECO:0000305} - LDLR chaperone MESD - Mesoderm development LRP chaperone MESD {ECO:0000312|HGNC:HGNC:13520} - Mesoderm development candidate 2 - Mesoderm development protein - Renal carcinoma antigen NY-REN-61 |
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Gene names | MESDC2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q14696 |
7
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAASRWARKA VVLLCASDLL LLLLLLPPPG SCAAEGSPGT PDESTPPPRK KKKDIRDYND
70 80 90 100 110 120
ADMARLLEQW EKDDDIEEGD LPEHKRPSAP VDFSKIDPSK PESILKMTKK GKTLMMFVTV
130 140 150 160 170 180
SGSPTEKETE EITSLWQGSL FNANYDVQRF IVGSDRAIFM LRDGSYAWEI KDFLVGQDRC
190 200 210 220 230
ADVTLEGQVY PGKGGGSKEK NKTKQDKGKK KKEGDLKSRS SKEENRAGNK REDL
Isoforms
- Isoform 2 of LRP chaperone MESDSequence View
10 20 30 40 50 60
MAASRWARKA VVLLCASDLL LLLLLLPPPG SCAAEGSPGT PDESTPPPRK KKKDIRDYND
70 80 90 100 110 120
ADMARLLEQW EKDDDIEEGD LPEHKRPSAP VDFSKIDPSK PESILKMTKK GKTLMMFVTV
130 140 150 160 170 180
SGSPTEKETE EITSLWQGSL FNANYDVQRF IVGSDRAIFM LRDGSYAWEI KDFLVGQDRC
190 200 210 220 230
ADVTLEGQVY PGKGGGSKEK NKTKQDKGKK KKEGDLKSRS SKEENRAGNK REDL
Protein Neighborhood
Domains & Features
7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q14696-30- | GSCAAE... | 30 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q14696-33-unknown | AAEGSP... | 33 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q14696-33-unknown | AAEGSP... | 33 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | THP_untreated | 23264352 | |||
Q14696-33- | AAEGSP... | 33 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q14696-34- | AEGSPG... | 34 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q14696-34- | AEGSPG... | 34 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q14696-34- | AEGSPG... | 34 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
Q14696-34-unknown | AEGSPG... | 34 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q14696-39- | GTPDES... | 39 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q14696-39- | GTPDES... | 39 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q14696-39-unknown | GTPDES... | 39 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...KREDL | 234 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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