Q15102: Platelet-activating factor acetylhydrolase IB subunit gamma

General Information

Protein names	- Platelet-activating factor acetylhydrolase IB subunit gamma - 3.1.1.47 - PAF acetylhydrolase 29 kDa subunit - PAF-AH 29 kDa subunit - PAF-AH subunit gamma - PAFAH subunit gamma
Gene names	PAFAH1B3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15102

7 N-termini

7 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGEENPASK PTPVQDVQGD GRWMSLHHRF VADSKDKEPE VVFIGDSLVQ LMHQCEIWRE
        70         80         90        100        110        120
LFSPLHALNF GIGGDGTQHV LWRLENGELE HIRPKIVVVW VGTNNHGHTA EQVTGGIKAI
       130        140        150        160        170        180
VQLVNERQPQ ARVVVLGLLP RGQHPNPLRE KNRQVNELVR AALAGHPRAH FLDADPGFVH
       190        200        210        220        230
SDGTISHHDM YDYLHLSRLG YTPVCRALHS LLLRLLAQDQ GQGAPLLEPA P

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 7 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15102-2-unknown	MSGEEN...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15102-2-	SGEENP...	2			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q15102-2-Acetylation	SGEENP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15102-2-Acetylation	SGEENP...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15102-2-Acetylation	SGEENP...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q15102-2-Acetylation	SGEENP...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q15102-3-acetylation	GEENPA...	3	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q15102-103-unknown	TNNHGH...	103		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6443
Q15102-133-acetylation	VVVLGL...	133	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q15102-142-unknown	GQHPNP...	142		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6444

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...HIRPKI	95	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469352
...IRPKIV	96	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000472950
...VVWVGT	102	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6443
...GLLPRG	141	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6444
...RAALAG	164	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000473065
...LEPAP	231		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LEPAP	231	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LEPAP	231		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	102	WVGT.\|.TNNH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	141	LPRG.\|.GQHP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)