Q562R1: Beta-actin-like protein 2

General Information

Protein names	- Beta-actin-like protein 2 - Kappa-actin
Gene names	ACTBL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q562R1

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTDNELSALV VDNGSGMCKA GFGGDDAPRA VFPSMIGRPR HQGVMVGMGQ KDCYVGDEAQ
        70         80         90        100        110        120
SKRGVLTLKY PIEHGVVTNW DDMEKIWYHT FYNELRVAPD EHPILLTEAP LNPKINREKM
       130        140        150        160        170        180
TQIMFEAFNT PAMYVAIQAV LSLYASGRTT GIVMDSGDGV THIVPIYEGY ALPHAILRLD
       190        200        210        220        230        240
LAGRDLTDYL MKILTERGYN FTTTAEREIV RDVKEKLCYV ALDFEQEMVR AAASSSPERS
       250        260        270        280        290        300
YELPDGQVIT IGNERFRCPE AIFQPSFLGI ESSGIHETTF NSIMKCDVDI RKDLYANTVL
       310        320        330        340        350        360
SGGSTMYPGI ADRMQKEIIT LAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
       370
QEYDEAGPPI VHRKCF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q562R1-1-unknown	MTDNEL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q562R1-21-	GFGGDD...	21		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q562R1-53-	CYVGDE...	53		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q562R1-53-	CYVGDE...	53		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q562R1-97-	VAPDEH...	97		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q562R1-97-	VAPDEH...	97		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q562R1-197-	RGYNFT...	197		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q562R1-246-unknown	GQVITI...	246	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2252

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YELPDG	245	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2252
	...HRKCF	376	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	245	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)