Q569Z6: Thyroid hormone receptor-associated protein 3

General Information

Protein names	- Thyroid hormone receptor-associated protein 3 - Thyroid hormone receptor-associated protein complex 150 kDa component - Trap150
Gene names	Thrap3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q569Z6

7 N-termini

9 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSVSRS RKRRLSSRSR SRSYSPAHNR
        70         80         90        100        110        120
ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP
       130        140        150        160        170        180
RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSTKEK
       190        200        210        220        230        240
KSSSKDSRPS QAAGDNQGDE AKEQTFSGGT SQDIKGSESS KPWPDATTYG AGSASRASVS
       250        260        270        280        290        300
DLSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSNA SQMGSSMSGG AGYQSGAHQG
       310        320        330        340        350        360
QFDHGSGSLS PSKKSPVGKS PPATGSAYGS SQKEESAASG GAAYSKRYLE EQKTENGKDK
       370        380        390        400        410        420
EQKQTNADKE KLKEKGGFSD ADVKMKSDPF APKTDSEKPF RGSQSPKRYK LRDDFEKKMA
       430        440        450        460        470        480
DFHKEELDEH DKDKSKGRKE PEFDDEPKFM SKVIAGASKN QEEEKSGKWE SLHTGKEKQR
       490        500        510        520        530        540
KAEEMEDEPF TERSRKEERG GSKRSESGHR GFVPEKNFRV TAYKAVQEKS SSPPPRKTSE
       550        560        570        580        590        600
SRDKLGSKGD FSSGKSSFSI TREAQVNVRM DSFDEDLARP SGLLAQERKL CRDLVHSNKK
       610        620        630        640        650        660
EQEFRSIFQH IQSAQSQRSP SELFAQHIVT IVHHVKEHHF GSSGMTLHER FTKYLKRGNE
       670        680        690        700        710        720
QEAAKNKKSP EIHRRIDISP STFRKHGLTH EELKSPREPG YKAEGKYKDD PVDLRLDIER
       730        740        750        760        770        780
RKKHKERDLK RGKSRESVDS RDSSHSRERS TEKTEKTHKG SKKQKKHRRA RDRSRSSSSS
       790        800        810        820        830        840
SQSSHSYKAE EYPEEAEERE ESTSGFDKSR LGTKDFVGPN ERGGRARGTF QFRARGRGWG
       850        860        870        880        890        900
RGNYSGNNNN NSNNDFQKRS REEEWDPEYT PKSKKYYLHD DREGEGSDKW MGRGRGRGAF
       910        920        930        940        950
PRGRGRFMFR KSSTSPKWAH DKFSGEEGEI EDDESGTENR EEKDSLQPSA E

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 9 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q569Z6-2-unknown	MSKTNK...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q569Z6-2-unknown	MSKTNK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q569Z6-2-Acetylation	SKTNKS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q569Z6-2-Acetylation	SKTNKS...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q569Z6-8-unknown	KSGSRS...	8		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q569Z6-44-unknown	RLSSRS...	44		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q569Z6-358-unknown	KDKEQK...	358		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000126399
Q569Z6-787-unknown	YKAEEY...	787		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33915
Q569Z6-875-unknown	KYYLHD...	875			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RSRSRS	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000101747
...RSRSFS	27	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118414
...RSFSKS	29	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120455
...SSRSRS	50	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000125856
...SRSRSY	53	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120140
...NEQEAA	663	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126399
...QSSHSY	786	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33915
...AFPRGR	903	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000129775
...QPSAE	951	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	786	SHSY.\|.YKAE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)