Q5JTV8: Torsin-1A-interacting protein 1

General Information

Protein names	- Torsin-1A-interacting protein 1 - Lamin-associated protein 1B - LAP1B
Gene names	TOR1AIP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5JTV8

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Torsin-1A-interacting protein 1 - Isoform 2 of Torsin-1A-interacting protein 1 - Isoform 3 of Torsin-1A-interacting protein 1

Sequence View

        10         20         30         40         50         60
MAGDGRRAEA VREGWGVYVT PRAPIREGRG RLAPQNGGSS DAPAYRTPPS RQGRREVRFS
        70         80         90        100        110        120
DEPPEVYGDF EPLVAKERSP VGKRTRLEEF RSDSAKEEVR ESAYYLRSRQ RRQPRPQETE
       130        140        150        160        170        180
EMKTRRTTRL QQQHSEQPPL QPSPVMTRRG LRDSHSSEED EASSQTDLSQ TISKKTVRSI
       190        200        210        220        230        240
QEAPVSEDLV IRLRRPPLRY PRYEATSVQQ KVNFSEEGET EEDDQDSSHS SVTTVKARSR
       250        260        270        280        290        300
DSDESGDKTT RSSSQYIESF WQSSQSQNFT AHDKQPSVLS SGYQKTPQEW APQTARIRTR
       310        320        330        340        350        360
MQNDSILKSE LGNQSPSTSS RQVTGQPQNA SFVKRNRWWL LPLIAALASG SFWFFSTPEV
       370        380        390        400        410        420
ETTAVQEFQN QMNQLKNKYQ GQDEKLWKRS QTFLEKHLNS SHPRSQPAIL LLTAARDAEE
       430        440        450        460        470        480
ALRCLSEQIA DAYSSFRSVR AIRIDGTDKA TQDSDTVKLE VDQELSNGFK NGQNAAVVHR
       490        500        510        520        530        540
FESFPAGSTL IFYKYCDHEN AAFKDVALVL TVLLEEETLG TSLGLKEVEE KVRDFLKVKF
       550        560        570        580
TNSNTPNSYN HMDPDKLNGL WSRISHLVLP VQPENALKRG ICL         10         20         30         40         50         60
MAGDGRRAEA VREGWGVYVT PRAPIREGRG RLAPQNGGSS DAPAYRTPPS RQGRREVRFS
        70         80         90        100        110        120
DEPPEVYGDF EPLVAKERSP VGKRTRLEEF RSDSAKEEVR ESAYYLRSRQ RRQPRPQETE
       130        140        150        160        170        180
EMKTRRTTRL QQQHSEQPPL QPSPVMTRRG LRDSHSSEED EASSQTDLSQ TISKKTVRSI
       190        200        210        220        230        240
QEAPVSEDLV IRLRRPPLRY PRYEATSVQQ KVNFSEEGET EEDDQDSSHS SVTTVKARSR
       250        260        270        280        290        300
DSDESGDKTT RSSSQYIESF WQSSQSQNFT AHDKQPSVLS SGYQKTPQEW APQTARIRTR
       310        320        330        340        350        360
MQNDSILKSE LGNQSPSTSS RQVTGQPQNA SFVKRNRWWL LPLIAALASG SFWFFSTPEV
       370        380        390        400        410        420
ETTAVQEFQN QMNQLKNKYQ GQDEKLWKRS QTFLEKHLNS SHPRSQPAIL LLTAARDAEE
       430        440        450        460        470        480
ALRCLSEQIA DAYSSFRSVR AIRIDGTDKA TQDSDTVKLE VDQELSNGFK NGQNAAVVHR
       490        500        510        520        530        540
FESFPAGSTL IFYKYCDHEN AAFKDVALVL TVLLEEETLG TSLGLKEVEE KVRDFLKVKF
       550        560        570        580
TNSNTPNSYN HMDPDKLNGL WSRISHLVLP VQPENALKRG ICL         10         20         30         40         50         60
MAGDGRRAEA VREGWGVYVT PRAPIREGRG RLAPQNGGSS DAPAYRTPPS RQGRREVRFS
        70         80         90        100        110        120
DEPPEVYGDF EPLVAKERSP VGKRTRLEEF RSDSAKEEVR ESAYYLRSRQ RRQPRPQETE
       130        140        150        160        170        180
EMKTRRTTRL QQQHSEQPPL QPSPVMTRRG LRDSHSSEED EASSQTDLSQ TISKKTVRSI
       190        200        210        220        230        240
QEAPVSEDLV IRLRRPPLRY PRYEATSVQQ KVNFSEEGET EEDDQDSSHS SVTTVKARSR
       250        260        270        280        290        300
DSDESGDKTT RSSSQYIESF WQSSQSQNFT AHDKQPSVLS SGYQKTPQEW APQTARIRTR
       310        320        330        340        350        360
MQNDSILKSE LGNQSPSTSS RQVTGQPQNA SFVKRNRWWL LPLIAALASG SFWFFSTPEV
       370        380        390        400        410        420
ETTAVQEFQN QMNQLKNKYQ GQDEKLWKRS QTFLEKHLNS SHPRSQPAIL LLTAARDAEE
       430        440        450        460        470        480
ALRCLSEQIA DAYSSFRSVR AIRIDGTDKA TQDSDTVKLE VDQELSNGFK NGQNAAVVHR
       490        500        510        520        530        540
FESFPAGSTL IFYKYCDHEN AAFKDVALVL TVLLEEETLG TSLGLKEVEE KVRDFLKVKF
       550        560        570        580
TNSNTPNSYN HMDPDKLNGL WSRISHLVLP VQPENALKRG ICL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q5JTV8-1-unknown	MAGDGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q5JTV8-1-unknown	MAGDGR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92741
Q5JTV8-122-unknown	MKTRRT...	122	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q5JTV8-122-unknown	MKTRRT...	122	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197263
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q5JTV8-227-	SSHSSV...	227		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q5JTV8-227-unknown	SSHSSV...	227		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q5JTV8-227-unknown	SSHSSV...	227	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162230
Q5JTV8-305-	SILKSE...	305		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q5JTV8-305-	SILKSE...	305		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q5JTV8-309-	SELGNQ...	309		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q5JTV8-309-	SELGNQ...	309		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q5JTV8-309-	SELGNQ...	309		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RGICL	583	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...RGICL	583	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt88359

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)