Q60631: Growth factor receptor-bound protein 2

General Information

Protein names	- Growth factor receptor-bound protein 2 - Adapter protein GRB2 - SH2/SH3 adapter GRB2
Gene names	Grb2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q60631

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW
        70         80         90        100        110        120
FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL
       130        140        150        160        170        180
WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQMPQQPTY VQALFDFDPQ EDGELGFRRG
       190        200        210
DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV

Isoforms

- Isoform 2 of Growth factor receptor-bound protein 2

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q60631-1-unknown	MEAIAK...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76405
Q60631-1-Acetylation	MEAIAK...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q60631-1-Acetylation	MEAIAK...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108082
Q60631-164-unknown	LFDFDP...	164		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33920
Q60631-164-unknown	LFDFDP...	164		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143608
Q60631-165-unknown	FDFDPQ...	165		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29132
Q60631-165-unknown	FDFDPQ...	165		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143672

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TYVQAL	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33920
...TYVQAL	163	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126850
...YVQALF	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29132
...YVQALF	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126915
...VNRNV	217	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VNRNV	217	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72023

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	163	VQAL.\|.LFDF	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> GRB2_MOUSE @163
CATD_MOUSE	164	QALF.\|.FDFD	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> GRB2_MOUSE @164

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)