Q61171: Peroxiredoxin-2

General Information

Protein names	- Peroxiredoxin-2 - 1.11.1.15 - Thiol-specific antioxidant protein - TSA - Thioredoxin peroxidase 1 - Thioredoxin-dependent peroxide reductase 1
Gene names	Prdx2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61171

7 N-termini

7 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASGNAQIGK SAPDFTATAV VDGAFKEIKL SDYRGKYVVL FFYPLDFTFV CPTEIIAFSD
        70         80         90        100        110        120
HAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTKS LSQNYGVLKN
       130        140        150        160        170        180
DEGIAYRGLF IIDAKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS
       190
DTIKPNVDDS KEYFSKHN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 7 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q61171-2-unknown	MASGNA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61171-2-Acetylation	ASGNAQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61171-55-unknown	IIAFSD...	55		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33938
Q61171-105-unknown	ADVTKS...	105		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29143
Q61171-114-unknown	NYGVLK...	114		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33939
Q61171-131-unknown	IIDAKG...	131		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29144
Q61171-141-unknown	ITVNDL...	141		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33940

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VCPTEI	54	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33938
...NIPLLA	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29143
...KSLSQN	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33939
...YRGLFI	130	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29144
...GVLRQI	140	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33940
...TVNDLP	146	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122694
...FSKHN	198	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	54	PTEI.\|.IIAF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	104	PLLA.\|.ADVT	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PRDX2_MOUSE @104
MMP2_MOUSE	113	LSQN.\|.NYGV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	130	GLFI.\|.IIDA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PRDX2_MOUSE @130
MMP2_MOUSE	140	LRQI.\|.ITVN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)