Q62446: Peptidyl-prolyl cis-trans isomerase FKBP3

General Information

Protein names	- Peptidyl-prolyl cis-trans isomerase FKBP3 - PPIase FKBP3 - 5.2.1.8 - 25 kDa FK506-binding protein - 25 kDa FKBP - FKBP-25 - FK506-binding protein 3 - FKBP-3 - Immunophilin FKBP25 - Rapamycin-selective 25 kDa immunophilin - Rotamase
Gene names	Fkbp3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q62446

4 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAVPQRAW TVEQLRSEQL PKKDIIKFLQ DHGSDSFLAE HKLLGNIKNV AKTANKDHLV
        70         80         90        100        110        120
NAYNHLFESK RFKGTETISK VSEQVKNVKL SDDKPKDSKS EETLDEGPPK YTKSILKKGD
       130        140        150        160        170        180
KTNFPKKGDV VHCWYTGTLP DGTVFDTNIQ TSSKKKKNAK PLSFKVGVGK VIRGWDEALL
       190        200        210        220
TMSKGEKARL EIEPEWAYGK KGQPDAKIPP NTKLIFEVEL VDID

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q62446-2-unknown	MAAAVP...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q62446-2-unknown	MAAAVP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q62446-2-Acetylation	AAAVPQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q62446-2-Acetylation	AAAVPQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q62446-164-unknown	FKVGVG...	164		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33997
Q62446-180-unknown	LTMSKG...	180		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30556
Q62446-180-unknown	LTMSKG...	180		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29177

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AKPLSF	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33997
...WDEALL	179	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30556
...WDEALL	179	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29177
...LVDID	224	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	163	PLSF.\|.FKVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	179	EALL.\|.LTMS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> FKBP3_MOUSE @179
CATD_MOUSE	179	EALL.\|.LTMS	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> FKBP3_MOUSE @179

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)