Q6IRU2: Tropomyosin alpha-4 chain

General Information

Protein names	- Tropomyosin alpha-4 chain - Tropomyosin-4
Gene names	Tpm4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6IRU2

7 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGLNSLEAV KRKIQALQQQ ADDAEDRAQG LQRELDGERE RREKAEGDAA ALNRRIQLLE
        70         80         90        100        110        120
EELDRAQEQL ATALQNLEEA EKAADESERG MKVIENRAMK DEEKMEILEM QLKEAKHITD
       130        140        150        160        170        180
EADRKYEEVA RKLVILEGEL KRAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE
       190        200        210        220        230        240
KEDKYEEEIK LLSDKLKEAE TRAEFAERTV SKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ

TLNELNCI

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6IRU2-2-unknown	MAGLNS...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q6IRU2-2-unknown	MAGLNS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6IRU2-2-Acetylation	AGLNSL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6IRU2-2-Acetylation	AGLNSL...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q6IRU2-2-Acetylation	AGLNSL...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q6IRU2-4-unknown	LNSLEA...	4		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34011
Q6IRU2-12-unknown	RKIQAL...	12		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q6IRU2-17-unknown	LQQQAD...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34012
Q6IRU2-77-unknown	LEEAEK...	77		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34013
Q6IRU2-132-unknown	KLVILE...	132			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RKIQAL	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34012
...TALQNL	76	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34013
...ELNCI	248	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	3	MAGL.\|.LNSL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	16	IQAL.\|.LQQQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	76	LQNL.\|.LEEA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)