Q6NXR4: TELO2-interacting protein 2

General Information

Protein names	- TELO2-interacting protein 2
Gene names	TTI2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6NXR4

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MELDSALEAP SQEDSNLSEE LSHSAFGQAF SKILHCLARP EARRGNVKDA VLKDLGDLIE
        70         80         90        100        110        120
ATEFDRLFEG TGARLRGMPE TLGQVAKALE KYAAPSKEEE GGGDGHSEAA EKAAQVGLLF
       130        140        150        160        170        180
LKLLGKVETA KNSLVGPAWQ TGLHHLAGPV YIFAITHSLE QPWTTPRSRE VAREVLTSLL
       190        200        210        220        230        240
QVTECGSVAG FLHGENEDEK GRLSVILGLL KPDLYKESWK NNPAIKHVFS WTLQQVTRPW
       250        260        270        280        290        300
LSQHLERVLP ASLVISDDYQ TENKILGVHC LHHIVLNVPA ADLLQYNRAQ VLYHAISNHL
       310        320        330        340        350        360
YTPEHHLIQA VLLCLLDLFP ILEKTLHWKG DGARPTTHCD EVLRLILTHM EPEHRLLLRR
       370        380        390        400        410        420
TYARNLPAFV NRLGILTVRH LKRLERVIIG YLEVYDGPEE EARLKILETL KLLMQHTWPR
       430        440        450        460        470        480
VSCRLVVLLK ALLKLICDVA RDPNLTPESV KSALLQEATD CLILLDRCSQ GRVKGLLAKI
       490        500
PQSCEDRKVV NYIRKVQQVS EGAPYNGT

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6NXR4-1-unknown	MELDSA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6NXR4-5-	SALEAP...	5		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q6NXR4-5-	SALEAP...	5		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6NXR4-5-	SALEAP...	5		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q6NXR4-5-	SALEAP...	5		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6NXR4-5-	SALEAP...	5		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KEEEGG	101	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000428569
...PYNGT	508	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...PYNGT	508		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PYNGT	508		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)