Q6UXV4: MICOS complex subunit MIC27

General Information

Protein names	- MICOS complex subunit MIC27 - Apolipoprotein O-like - Protein FAM121A
Gene names	APOOL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6UXV4

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAIRMGKLT TMPAGLIYAS VSVHAAKQEE SKKQLVKPEQ LPIYTAPPLQ SKYVEEQPGH
        70         80         90        100        110        120
LQMGFASIRT ATGCYIGWCK GVYVFVKNGI MDTVQFGKDA YVYLKNPPRD FLPKMGVITV
       130        140        150        160        170        180
SGLAGLVSAR KGSKFKKITY PLGLATLGAT VCYPVQSVII AKVTAKKVYA TSQQIFGAVK
       190        200        210        220        230        240
SLWTKSSKEE SLPKPKEKTK LGSSSEIEVP AKTTHVLKHS VPLPTELSSE AKTKSESTSG
       250        260
ATQFMPDPKL MDHGQSHPED IDMYSTRS

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6UXV4-20-	SVSVHA...	20		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q6UXV4-20-unknown	SVSVHA...	20		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6UXV4-20-unknown	SVSVHA...	20		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6UXV4-28-unknown	QEESKK...	28	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YSTRS	268	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)