Q78PY7: Staphylococcal nuclease domain-containing protein 1
Protein names | - Staphylococcal nuclease domain-containing protein 1 - 3.1.31.1 {ECO:0000250|UniProtKB:Q7KZF4} - 100 kDa coactivator - p100 co-activator |
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Gene names | Snd1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q78PY7 |
13
N-termini
9
C-termini
8
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MASSAQSSGS SGGPAVPTVQ RGIVKMVLSG CAIIVRGQPR GGPPPERQIN LSNIRAGNLA
70 80 90 100 110 120
RRAAATQPDG KDTPDEPWAF PAREFLRKKL IGKEVCFTIE NKTPQGREYG MIYLGKDTNG
130 140 150 160 170 180
ENIAESLVAE GLATRREGMR ANNPEQNRLS ECEEQAKASK KGMWSEGNGS HTIRDLKYTI
190 200 210 220 230 240
ENPRHFVDSH HQKPVNAIIE HVRDGSVVRA LLLPGHHLVT VMLSGIKCPT FRRETDGSET
250 260 270 280 290 300
PEPFAAEAKF FTESRLLQRD VQIILESCHN QNLLGTILHP NGNITELLLK EGFARCVDWS
310 320 330 340 350 360
IAVYTRGAEK LRAAERFAKE RRLRIWRDYV PPTANLDQKD KQFVAKVMQV LNADAIVVKL
370 380 390 400 410 420
NSGDYKTIHL SSIRPPRLEG DNIQDKNKKL RPLYDIPYMF EAREFLRKKL IGKKVNVTVD
430 440 450 460 470 480
YIRPASPATE TVPAFSERTC ATVTIGGINI AEALVSKGLA TVIRYRQDDD QRSSHYDELL
490 500 510 520 530 540
AAEARAIKNG KGLHSKKEVP IHRVADISGD TQKAKQFLPF LQRAGRSEAV VEYVFSGSRL
550 560 570 580 590 600
KLYLPKETCL ITFLLAGIEC PRGARNLPGL VQEGEPFSEE ATLFTKELVL QREVEVEVES
610 620 630 640 650 660
MDKAGNFIGW LHMDGANLSV LLVEQALSKV HFTAERSAYY KPLLSAEEAA KQRKEKVWAH
670 680 690 700 710 720
YEERPVEEVM PVLEEKERSA SYKPVFVTEI TDDLHFYVQD VETGTQLEKL MENMRNDISS
730 740 750 760 770 780
HPPVEGSYAP RRGEFCIAKF VDGEWYRARV EKVESPAKVH VFYIDYGNRE ILPSTRLGTL
790 800 810 820 830 840
PPAFSTRVLP AQATEYAFAF IQVPQDEDAR TDAVDSVVRD IQNTQCLLNV EHLSASCPHV
850 860 870 880 890 900
TLQFADSKGD VGLGLVKEGL VMVEVRKEKQ FQKVITEYLN AQESAKSARL NLWRYGDFRA
910
DDADEFGYSR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
13 N-termini - 9 C-termini - 8 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q78PY7-2-unknown | MASSAQ... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q78PY7-2-unknown | MASSAQ... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q78PY7-2-Acetylation | ASSAQS... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q78PY7-2-Acetylation | ASSAQS... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q78PY7-98-unknown | TIENKT... | 98 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30656 | |||
Q78PY7-128-unknown | VAEGLA... | 128 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30657 | |||
Q78PY7-176-unmodified | LKYTIE... | 176 | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | |||
Q78PY7-186-unknown | FVDSHH... | 186 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34037 | |||
Q78PY7-223-unknown | LSGIKC... | 223 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30658 | |||
Q78PY7-253-unknown | ESRLLQ... | 253 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q78PY7-455-unknown | VSKGLA... | 455 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30659 | |||
Q78PY7-514-unmodified | AKQFLP... | 514 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
Q78PY7-643-unknown | LLSAEE... | 643 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34038 | |||
Q78PY7-669-unknown | VMPVLE... | 669 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30660 | |||
Q78PY7-801-unknown | IQVPQD... | 801 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34039 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...KEVCFT | 97 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30656 | |||
...IAESLV | 127 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30657 | |||
...ENPRHF | 185 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34037 | |||
...LVTVML | 222 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30658 | |||
...IAEALV | 454 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30659 | |||
...AYYKPL | 642 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34038 | |||
...RPVEEV | 668 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30660 | |||
...YAFAFI | 800 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34039 | |||
...FGYSR | 910 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 97 | VCFT.|.TIEN | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SND1_MOUSE @97 | ||
CATE_MOUSE | 127 | ESLV.|.VAEG | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SND1_MOUSE @127 | ||
MMP2_MOUSE | 185 | PRHF.|.FVDS | inferred from experiment | unknown | MEROPS | Overall CM | Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) | 20305284, |
CATE_MOUSE | 222 | TVML.|.LSGI | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SND1_MOUSE @222 | ||
CATE_MOUSE | 454 | EALV.|.VSKG | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SND1_MOUSE @454 | ||
MMP2_MOUSE | 642 | YKPL.|.LLSA | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
CATE_MOUSE | 668 | VEEV.|.VMPV | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SND1_MOUSE @668 | ||
MMP2_MOUSE | 800 | FAFI.|.IQVP | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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