Q7TNP2: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform - PP2A subunit A isoform PR65-beta - PP2A subunit A isoform R1-beta
Gene names	Ppp2r1b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q7TNP2

4 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGAAGPGSG PGAAGGDGDD SLYPIAVLID ELRNEDVQLR LNSIKKLSTI ALALGVERTR
        70         80         90        100        110        120
TELLPFLTDT IYDEDEVLLA LAEQLGNFTG LVGGPDFAHC LLPPLESLAT VEETVVRDKA
       130        140        150        160        170        180
VESLRQISQE HTPVALEAHF VPLVKRLASG DWFTSRTSAC GLFSVCYPRA SNAVKAEIRQ
       190        200        210        220        230        240
HFRSLCSDDT PMVRRAAASK LGEFAKVLEL DSVKTEIVPL FTNLASDEQD SVRLLAVEAC
       250        260        270        280        290        300
VSIAQLLSQE DLEALVMPTL RQAAEDKSWR VRYMVADKFS ELQKAVGPKI ALSDLIPAFQ
       310        320        330        340        350        360
SLLRDCEAEV RAAAAHKVRE LCENLPAEGR ETVIMNQILP YIKELVSDTN QHVKSALASV
       370        380        390        400        410        420
IMGLSTVLGK ENTIEHLLPL FLAQLKDECP EVRLNIISNL DCVNEVIGIR QLSQSLLPAI
       430        440        450        460        470        480
VELAEDAKWR VRLAIIEYMP LLAGQLGVEF FDEKLNSLCM AWLVDHVYAI REAATNNLMK
       490        500        510        520        530        540
LVQKFGTEWA QNTIVPKVLV MANDPNYLHR MTTLFCINAL SEACGKEITT KQMLPIVLKM
       550        560        570        580        590        600
AGDQVANVRF NVAKSLQKIG PILDTNALQG EVKPVLQKLG QDEDMDVKYF AQEAISVLAL

A

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q7TNP2-2-unknown	MAGAAG...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q7TNP2-2-unknown	MAGAAG...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7TNP2-2-Acetylation	AGAAGP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q7TNP2-2-Acetylation	AGAAGP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q7TNP2-109-unknown	ATVEET...	109		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29219
Q7TNP2-109-unknown	ATVEET...	109		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30678
Q7TNP2-224-unknown	LASDEQ...	224		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34045

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PLESLA	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29219
...PLESLA	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30678
...PLFTNL	223	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34045
...VLALA	601	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	108	ESLA.\|.ATVE	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	108	ESLA.\|.ATVE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> 2AAB_MOUSE @108
MMP2_MOUSE	223	FTNL.\|.LASD	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)