Q86U28: Iron-sulfur cluster assembly 2 homolog, mitochondrial

General Information

Protein names	- Iron-sulfur cluster assembly 2 homolog, mitochondrial - HESB-like domain-containing protein 1
Gene names	ISCA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86U28

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAWGSSLT AATQRAVTPW PRGRLLTASL GPQARREASS SSPEAGEGQI RLTDSCVQRL
        70         80         90        100        110        120
LEITEGSEFL RLQVEGGGCS GFQYKFSLDT VINPDDRVFE QGGARVVVDS DSLAFVKGAQ
       130        140        150
VDFSQELIRS SFQVLNNPQA QQGCSCGSSF SIKL

Isoforms

- Isoform 2 of Iron-sulfur cluster assembly 2 homolog, mitochondrial

Sequence View

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Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86U28-9-unknown	LTAATQ...	9	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86U28-38-unknown	ASSSSP...	38		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86U28-38-unknown	ASSSSP...	38		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q86U28-38-	ASSSSP...	38		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q86U28-39-	SSSSPE...	39		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86U28-39-	SSSSPE...	39		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q86U28-40-	SSSPEA...	40		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86U28-40-	SSSPEA...	40		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...FSIKL	154	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)